Jacob S. Young

Harvard University — United States

Medicine · Health Sciences

34h-index4.7kcitations273works3.52yr avg
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Research Topics

Glioma Diagnosis and Treatment(140), Meningioma and schwannoma management(58), Radiomics and Machine Learning in Medical Imaging(28), Brain Metastases and Treatment(26), Virus-based gene therapy research(23)

Publications271 total

The Intraoperative Utility of Raman Spectroscopy for Neurosurgical Oncology
Cancers·2025Open Access
A prognostic classification system for extent of resection in IDH-mutant grade 2 glioma: an international, multicentre, retrospective cohort study with external validation by the RANO resect group
The Lancet Oncology·2025· 4 citedOpen Access
A systematic review of trial-matching pipelines using large language models
2025· 2 citedOpen Access
EXTH-123. Novel Dyrk1a inhibitors impair glioblastoma proliferation and enhance the effectiveness of other cell-cycle-directed therapies
Neuro-Oncology·2025Open Access
INNV-27. A coordinated care model for multidisciplinary meningioma treatment and research
Neuro-Oncology·2025Open Access
CNSC-98. SYNAPTIC REMODELING DRIVES IDH-MUTANT ASTROCYTOMA PROGRESSION AND EVOLUTION
Neuro-Oncology·2025
PATH-82. Multivariate survival risk stratification in GBMs lacking necrosis and microvascular proliferation
Neuro-Oncology·2025Open Access
CNSC-15. TARGETING GLIOMA-NEURONAL CIRCUIT REMODELING TO OVERCOME IMMUNOSUPPRESSION: FUNCTIONAL AND THERAPEUTIC INSIGHTS
Neuro-Oncology·2025Open Access
SURG-100. The favorable associations between age and supramaximal resection with outcome in glioblastoma – a report of the RANO resect group
Neuro-Oncology·2025Open Access
SURG-79. A prognostic classification system for extent of resection in IDH-mutant grade 2 glioma: an international, multicenter, retrospective study with external validation by the RANO resect group
Neuro-Oncology·2025
BIOM-19. GENE EXPRESSION BIOMARKER PREDICTION OF BENEFIT FROM RE-IRRADIATION IN RECURRENT GLIOBLASTOMA
Neuro-Oncology·2025Open Access
TIP-08. Trial in progress update: A phase 1/2 study of intracranial and intravenous multi-dosing of DB107-RRV (formerly Toca 511) and DB107-FC (5-fluorocytosine) in combination with radiation ± temozolomide (TMZ) in patients with newly diagnosed high-grade gliomas (HGGs)
Neuro-Oncology·2025Open Access
PATH-81. DNA sequencing identifies NF1 variant classes associated with malignant peripheral nerve sheath tumor (MPNST) formation in neurofibromatosis type I
Neuro-Oncology·2025Open Access
SURG-83. Inter-rater agreement from an international expert panel on resectability of recurrent glioblastoma: a complementary post-hoc analysis of the prospective, randomized DIRECTOR trial
Neuro-Oncology·2025Open Access
Reflecting on Scientific Growth and Innovation as the Society for Neuro-Oncology Turns 30
Neuro-Oncology·2025
Blood Ethanol Level Influences Presenting Glasgow Coma Scale Interpretation After Traumatic Brain Injury: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study
Neurosurgery·2025
Associations of supramaximal resection with outcome in glioblastoma across age groups: A report of the RANO <i>resect</i> group
Neuro-Oncology·2025· 1 cited
P07.10.B INTER-RATER AGREEMENT FROM A MULTI-NATIONAL EXPERT PANEL ON RESECTABILITY OF RECURRENT GLIOBLASTOMA: A COMPLEMENTARY POST-HOC ANALYSIS OF THE PROSPECTIVE, RANDOMIZED DIRECTOR TRIAL
Neuro-Oncology·2025Open Access
P02.02.A IL6 UNDERLIES MICROENVIRONMENT IMMUNOSUPPRESSION AND RESISTANCE TO THERAPY IN GLIOBLASTOMA
Neuro-Oncology·2025Open Access
OS11.6.A A COMPREHENSIVE FRAMEWORK FOR INTRAOPERATIVE MAPPING AND MONITORING, AND PERIOPERATIVE NEUROLOGICAL, LINGUISTIC, AND OUTCOME ASSESSMENT IN GLIOMA RESECTION: CONSENSUS RECOMMENDATIONS FROM THE PIONEER CONSORTIUM AND RANO RESECT GROUP
Neuro-Oncology·2025Open Access
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Frequent Co-authors

Mitchel S. Berger(32), Ramin A. Morshed(22), Shawn L. Hervey‐Jumper(21), Manish K. Aghi(15), Alexander F. Haddad(10), Annette M. Molinaro(9), Edward F. Chang(8), Javier Villanueva-Meyer(8), Nicholas Butowski(7), Philip V. Theodosopoulos(7), Nancy Ann Oberheim Bush(6), Andrew Gogos(6), Jennie Taylor(5), Jennifer Clarke(5), Yalan Zhang(4), Joanna J. Phillips(4), Susan M. Chang(4), Philipp Karschnia(4), Michael Weller(4), Roberta Rudà(4)