Malcolm E. Winkler

Indiana University Bloomington — United States

Medicine · Health Sciences

62h-index11.0kcitations177works3.52yr avg
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Research Topics

Pneumonia and Respiratory Infections(57), Bacterial Genetics and Biotechnology(56), RNA and protein synthesis mechanisms(54), RNA modifications and cancer(28), Bacterial Infections and Vaccines(23)

Publications177 total

Pneumococcal S protein coordinates cell wall modification and repair to resist host antimicrobials
Nature Microbiology·2025· 1 cited
Uncovering the Biological Function of the Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae
2025Open Access
Glycosylation of serine/threonine-rich intrinsically disordered regions of membrane-associated proteins in streptococci
Nature Communications·2025· 5 citedOpen Access
Light-dependent modulation of protein localization and function in living bacteria cells
Nature Communications·2024· 5 citedOpen Access
A bacterial cell wall repair and modification system to resist host antibacterial factors
2024· 2 citedOpen Access
The five homologous CiaR-controlled Ccn sRNAs of Streptococcus pneumoniae modulate Zn-resistance
PLoS Pathogens·2024· 3 citedOpen Access
Light-dependent modulation of protein localization and function in living bacteria cells
2024Open Access
GpsB Coordinates StkP Signaling as a PASTA Kinase Adaptor in Streptococcus pneumoniae Cell Division
Journal of Molecular Biology·2024· 4 citedOpen Access
Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of <i>Streptococcus pneumoniae</i>
Proceedings of the National Academy of Sciences·2024· 12 citedOpen Access
Glycosylation of serine/threonine-rich intrinsically disordered regions of membrane-associated proteins in streptococci
2024· 1 citedOpen Access
Alternate routes to mnm <sup>5</sup> s <sup>2</sup> U synthesis in Gram-positive bacteria
Journal of Bacteriology·2024· 8 citedOpen Access
Elongasome core proteins and class A PBP1a display zonal, processive movement at the midcell of <i>Streptococcus pneumoniae</i>
2024· 1 citedOpen Access
Alternate routes to mnm <sup>5</sup> s <sup>2</sup> U synthesis in Gram-positive bacteria
2023· 2 citedOpen Access
Secrets of getting started: Regulation of the first committed step of peptidoglycan synthesis by protein phosphorylation in <i>Enterococcus</i> and other Gram‐positive bacteria
Molecular Microbiology·2023· 2 citedOpen Access
The five homologous CiaR-controlled Ccn sRNAs of <i>Streptococcus pneumoniae</i> modulate Zn-resistance
2023Open Access
Negative regulation of <scp>MurZ</scp> and <scp>MurA</scp> underlies the essentiality of <scp>GpsB</scp> ‐ and <scp>StkP</scp> ‐mediated protein phosphorylation in <i>Streptococcus pneumoniae</i> <scp>D39</scp>
Molecular Microbiology·2023· 16 citedOpen Access
Chromosomal Duplications of MurZ (MurA2) or MurA (MurA1), Amino Acid Substitutions in MurZ (MurA2), and Absence of KhpAB Obviate the Requirement for Protein Phosphorylation in <i>Streptococcus pneumoniae</i> D39
2023· 1 citedOpen Access
Roles of <scp>RodZ</scp> and class A <scp>PBP1b</scp> in the assembly and regulation of the peripheral peptidoglycan elongasome in ovoid‐shaped cells of <i>Streptococcus pneumoniae</i> <scp>D39</scp>
Molecular Microbiology·2022· 18 citedOpen Access
Roles of RodZ and Class A PBP1b in the Assembly and Regulation of the Peripheral Peptidoglycan Elongasome in Ovoid-Shaped Cells of <i>Streptococcus pneumoniae</i> D39
2022Open Access
SifR is an Rrf2-family quinone sensor associated with catechol iron uptake in Streptococcus pneumoniae D39
Journal of Biological Chemistry·2022· 13 citedOpen Access
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Frequent Co-authors

Ho‐Ching Tiffany Tsui(14), Krystyna M. Kazmierczak(10), Wai‐Leung Ng(9), Lok‐To Sham(7), Gregory T. Robertson(6), Genshi Zhao(5), Raymond Gilmour(4), Ozden Kocaoglu(4), Erin E. Carlson(4), Kyle J. Wayne(3), Gang Feng(3), Amilcar J. Perez(3), Sidney L. Shaw(3), Michael J. Boersma(3), David Giedroc(3), Adrian D. Land(3), Jia-Qi Zheng(3), Orietta Massidda(3), John I. Glass(2), Hon‐Chiu Eastwood Leung(2)