William E. Cotham

University of South Carolina — United States

Earth and Planetary Sciences · Physical Sciences

18h-index1.4kcitations40works1.12yr avg
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Research Topics

Atmospheric chemistry and aerosols(5), Toxic Organic Pollutants Impact(5), Estrogen and related hormone effects(5), Metabolism and Genetic Disorders(5), Mitochondrial Function and Pathology(4)

Publications40 total

Region-Specific Quantification of 2-Hydroxyglutarate Enantiomers in Murine Brain during Mitochondrial Complex I Deficiency
ACS Chemical Neuroscience·2025
Adipose Tissue Estrogen Receptor-Alpha Overexpression Ameliorates High-Fat Diet–Induced Adipose Tissue Inflammation
Journal of the Endocrine Society·2025· 3 citedOpen Access
Abstract 2779 Quantification of 2-Hydroxyglutarate Enantiomers in the Ndufs4 Knockout Mouse
Journal of Biological Chemistry·2025Open Access
Cyclopropanol - A Caged Dual-Functional Warhead for Selective Electrochemical Bioconjugation
2025Open Access
Electrophilic Cysteine Adducts Associated with Immunomodulation in Mitochondrial Disease Model
Free Radical Biology and Medicine·2024
Quantification of 2-Hydroxyglutarate Enantiomers in the Ndufs4 Knockout Mouse
Free Radical Biology and Medicine·2024
Conformational Plasticity Enhances the Brain Penetration of a Metabolically Stable, Dual-Functional Opioid-Peptide CycloAnt
International Journal of Molecular Sciences·2024· 1 citedOpen Access
The deuterated glucose insulin tolerance test: a new tool to delineate insulin-stimulated glucose uptake from suppression of endogenous glucose production
Life Metabolism·2024· 1 citedOpen Access
Quantification of the immunometabolite protein modifications S-2-succinocysteine and 2,3-dicarboxypropylcysteine
American Journal of Physiology-Endocrinology and Metabolism·2024· 5 citedOpen Access
A Novel Tissue-Specific Insight into Sex Steroid Fluctuations Throughout the Murine Estrous Cycle
Endocrinology·2023· 11 citedOpen Access
Defective function of α-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiency
Redox Biology·2023· 18 citedOpen Access
Skeletal Muscle Endogenous Estrogen Production Ameliorates the Metabolic Consequences of a High-Fat Diet in Male Mice
Endocrinology·2023· 12 citedOpen Access
Augmenting Skeletal Muscle Estrogen Does not Prevent or Rescue Obesity-linked Metabolic Impairments in Female Mice
Endocrinology·2022· 7 citedOpen Access
Succination of Dihydrolipoyllysine Succinyltransferase by Fumarate Reduces α-Ketoglutarate Dehydrogenase Activity and Exacerbates Mitochondrial ATP Deficits in the Ndufs4 Knockout Model of Leigh Syndrome
Free Radical Biology and Medicine·2022
Design, synthesis and analysis of novel sphingosine kinase-1 inhibitors to improve oral bioavailability
Bioorganic & Medicinal Chemistry Letters·2021· 2 citedOpen Access
Extracts of select endemic plants from the Republic of Mauritius exhibiting anti-cancer and immunomodulatory properties
Scientific Reports·2021· 21 citedOpen Access
Safety of natural anthraquinone emodin: an assessment in mice
BMC Pharmacology and Toxicology·2021· 38 citedOpen Access
Defective Function of α-Ketoglutarate Dehydrogenase Exacerbates Mitochondrial ATP Deficits during Complex I Deficiency
2020· 1 citedOpen Access
GSK‐3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility
Traffic·2015· 58 citedOpen Access
Identification of protein succination as a novel modification of tubulin
Biochemical Journal·2014· 48 cited
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Frequent Co-authors

Michael D. Walla(18), Gerardo G. Piroli(9), Norma Frizzell(9), Terry F. Bidleman(8), Richard McCain(8), Jonathan W. C. Brock(6), Reilly T. Enos(6), Holland Smith(6), Suzanne R. Thorpe(5), John Baynes(5), Jennifer M. Ames(5), Christian Unger(5), Marion C Hope(5), Allison M. Manuel(4), Kandy T. Velázquez(4), Ahmed Al-Adhami(4), Davinia J. S. Hinton(3), Thomas Metz(3), Olivér Ozohanics(3), Attila Ambrus(3)