Stephanie Portillo‐Ledesma

Simons Foundation — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index1.1kcitations54works3.62yr avg
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Research Topics

Genomics and Chromatin Dynamics(36), RNA Research and Splicing(17), Chromosomal and Genetic Variations(12), Redox biology and oxidative stress(8), Epigenetics and DNA Methylation(5)

Publications54 total

Chromatin higher-order folding as influenced by preferred values of linker DNA
Current Opinion in Structural Biology·2025· 4 citedOpen Access
The influence of <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif"> <mml:mrow> <mml:mn>10</mml:mn> <mml:mi>n</mml:mi> </mml:mrow> </mml:math> and <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si2.gif"> <mml:mrow> <mml:mn>10</mml:mn> <mml:mi>n</mml:mi> <mml:mo linebreak="goodbreak" linebreakstyle="after">+</mml:mo> <mml:mn>5</mml:mn> </mml:mrow> </mml:math> linker lengths on chromatin fiber topologies explored by mesoscale modeling
Biophysical Journal·2025· 2 citedOpen Access
Molecular dynamics simulations reveal subtle consequences of H3K9 and H3K27 tri-methylation on chromatin constituents
Biophysical Journal·2025Open Access
Compromised two-start zigzag chromatin folding in immature mouse retina cells driven by irregularly spaced nucleosomes with short DNA linkers
Nucleic Acids Research·2025· 2 citedOpen Access
Regulation of Genome Architecture in Huntington’s Disease
Biochemistry·2025· 4 citedOpen Access
Incorporating multiscale methylation effects into nucleosome-resolution chromatin models for simulating mesoscale fibers
The Journal of Chemical Physics·2025· 5 cited
BPS2025 - Regulation of chromatin architecture associated to Huntington's disease: Role of the macroH2A1 histone variant
Biophysical Journal·2025
Compromised 2-start zigzag chromatin folding in immature mouse retina cells driven by irregularly spaced nucleosomes with short DNA linkers
2025Open Access
Structural insights into the cooperative nucleosome recognition and chromatin opening by FOXA1 and GATA4
Molecular Cell·2024· 11 citedOpen Access
Regulation of chromatin architecture by protein binding: insights from molecular modeling
Biophysical Reviews·2024· 4 citedOpen Access
Author Response: Regulation of chromatin architecture by transcription factor binding
2024Open Access
Regulation of chromatin architecture by transcription factor binding
eLife·2024· 11 citedOpen Access
Reviewer #1 (Public Review): Regulation of Chromatin Architecture by Transcription Factor Binding
2023Open Access
Regulation of Chromatin Architecture by Transcription Factor Binding
2023Open Access
Author Response: Regulation of Chromatin Architecture by Transcription Factor Binding
2023Open Access
Reviewer #2 (Public Review): Regulation of Chromatin Architecture by Transcription Factor Binding
2023Open Access
Regulation of Chromatin Architecture by Transcription Factor Binding
2023· 1 citedOpen Access
Regulation of chromatin architecture by transcription factor binding
eLife·2023· 12 citedOpen Access
Reviewer #1 (Public Review): Regulation of Chromatin Architecture by Transcription Factor Binding
2023Open Access
Regulation of Chromatin Architecture by Transcription Factor Binding
2023· 1 citedOpen Access
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Frequent Co-authors

Tamar Schlick(41), Suckwoo Chung(10), Jill M. Hoffman(10), Gerardo Ferrer‐Sueta(9), Zilong Li(9), Bruno Manta(4), Bernard Knoops(4), André Clippe(3), Luís Eduardo Soares Netto(3), Albert Mao(3), Carrie Chen(3), Florencia Sardi(2), E. Laura Coitiño(2), Maria Pia Cosma(2), Melike Lakadamyali(2), Carlos A. Tairum(2), Melina Cardoso dos Santos(2), Carlos Alexandre Breyer(2), Cecilia Nieves(2), Marcos Hikari Toyama(2)