Elvin D. de Araujo

University of Toronto — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.2kcitations75works2.62yr avg
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Research Topics

Protein Degradation and Inhibitors(20), Histone Deacetylase Inhibitors Research(19), Cytokine Signaling Pathways and Interactions(13), Peptidase Inhibition and Analysis(12), Chemical Synthesis and Analysis(10)

Publications75 total

Thyroid hormone receptor beta signaling is a targetable driver of prostate cancer growth
Molecular Cancer·2025Open Access
Improved Pharmacokinetic Profiles of HDAC6 Inhibitors via Cap Group Modifications
Journal of Medicinal Chemistry·2025· 1 cited
Allosteric Covalent Inhibitors of the STAT3 Transcription Factor from Virtual Screening
ACS Medicinal Chemistry Letters·2025· 2 citedOpen Access
Dual STAT3/STAT5 inhibition as a novel treatment strategy in T-prolymphocytic leukemia
Leukemia·2025· 3 citedOpen Access
Monoselective Histone Deacetylase 6 PROTAC Degrader Shows <i>In Vivo</i> Tractability
Journal of Medicinal Chemistry·2025· 13 cited
Thyroid Hormone Receptor Beta Signaling is a Targetable Driver of Prostate Cancer Growth
2025Open Access
Microwave-assisted synthesis of pomalidomide building blocks for rapid PROTAC and molecular glue development
Chemical Communications·2025
The structural influence of the oncogenic driver mutation <scp>N642H</scp> in the <scp>STAT5B SH2</scp> domain
Protein Science·2024· 1 citedOpen Access
Dual specific STAT3/5 degraders effectively block acute myeloid leukemia and natural killer/T cell lymphoma
HemaSphere·2024· 4 citedOpen Access
Rücktitelbild: Target‐Templated Construction of Functional Proteomimetics Using Photo‐Foldamer Libraries (Angew. Chem. 2/2025)
Angewandte Chemie·2024Open Access
Back Cover: Target‐Templated Construction of Functional Proteomimetics Using Photo‐Foldamer Libraries (Angew. Chem. Int. Ed. 2/2025)
Angewandte Chemie International Edition·2024Open Access
De novo GTP synthesis is a metabolic vulnerability for the interception of brain metastases
Cell Reports Medicine·2024· 6 citedOpen Access
Target‐Templated Construction of Functional Proteomimetics Using Photo‐Foldamer Libraries
Angewandte Chemie International Edition·2024· 7 citedOpen Access
Target‐Templated Construction of Functional Proteomimetics Using Photo‐Foldamer Libraries
Angewandte Chemie·2024· 1 citedOpen Access
The structural influence of the oncogenic driver mutation N642H in the STAT5B SH2 domain
2024Open Access
TRSC-04 DE NOVO GTP SYNTHESIS IS A METABOLIC VULNERABILITY FOR THE INTERCEPTION OF BRAIN METASTASES
Neuro-Oncology Advances·2024Open Access
Mapping protein binding sites by photoreactive fragment pharmacophores
Communications Chemistry·2024· 7 citedOpen Access
Chemical Proteomics-based Target Prioritization through a Residue Agnostic Ligandability Assessment Platform
2023· 1 citedOpen Access
Discovery of YSR734: A Covalent HDAC Inhibitor with Cellular Activity in Acute Myeloid Leukemia and Duchenne Muscular Dystrophy
Journal of Medicinal Chemistry·2023· 13 citedOpen Access
Small molecule STAT3/5 inhibitors exhibit therapeutic potential in acute myeloid leukemia and extra-nodal natural killer/T cell lymphoma
Research Square (Research Square)·2023· 1 citedOpen Access
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Frequent Co-authors

Patrick T. Gunning(40), Richard Moriggl(17), Pimyupa Manaswiyoungkul(13), Abootaleb Sedighi(13), Olasunkanmi O. Olaoye(11), Anna Orlova(10), Aaron D. Cabral(10), Heidi A. Neubauer(9), György M. Keserű(8), Marco Herling(8), Johan Israelian(8), Krimo Toutah(8), Nabanita Nawar(8), Yasir S. Raouf(8), Dávid Bajusz(7), Fettah Erdogan(7), Mulu Geletu(7), Tudor B. Radu(7), Gary Tin(6), Justyna M. Gawel(6)