Wynetta Giles‐Davis

The Wistar Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index2.0kcitations41works2.02yr avg
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Research Topics

Virus-based gene therapy research(27), Immunotherapy and Immune Responses(19), HIV Research and Treatment(7), CAR-T cell therapy research(7), Immune Cell Function and Interaction(6)

Publications41 total

Preclinical Immunogenicity and Efficacy Studies for Therapeutic Vaccines for Human Papillomavirus-Type-16-Associated Cancer
Vaccines·2024· 2 citedOpen Access
Treatment with the PPARα agonist fenofibrate improves the efficacy of CD8+ T cell therapy for melanoma
Molecular Therapy — Oncolytics·2023· 11 citedOpen Access
454 Checkpoint modification of early T cell activation provides enhanced anti-tumor activity and survival benefits in a fast-growing preclinical tumor challenge model
Regular and Young Investigator Award Abstracts·2023Open Access
Pre-clinical testing of two serologically distinct chimpanzee-origin adenovirus vectors expressing spike of SARS-CoV-2
Research Square (Research Square)·2023Open Access
Heterologous chimpanzee adenovirus vector immunizations for SARS-CoV-2 spike and nucleocapsid protect hamsters against COVID-19
Microbes and Infection·2022· 13 citedOpen Access
Prime-boost vaccinations with two serologically distinct chimpanzee adenovirus vectors expressing SARS-CoV-2 spike or nucleocapsid tested in a hamster COVID-19 model
2022Open Access
16P Checkpoint modification of BTLA-HVEM-LIGHT signaling by HSV-1 glycoprotein D (gD) improves vaccine-induced CD8+ T cell responses in pre-clinical cancer models
Annals of Oncology·2022· 1 cited
Pre-clinical testing of two serologically distinct chimpanzee-origin adenovirus vectors expressing spike of SARS-CoV-2
2022· 2 citedOpen Access
Pre-Clinical Testing of Two Serologically Distinct Chimpanzee-Origin Adenovirus Vectors Expressing Spike of SARS-CoV-2
SSRN Electronic Journal·2022Open Access
Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
Cancer Cell·2017· 583 citedOpen Access
A Partial <i>E3</i> Deletion in Replication-Defective Adenoviral Vectors Allows for Stable Expression of Potentially Toxic Transgene Products
Human Gene Therapy Methods·2016· 3 citedOpen Access
Abstract B49: Metabolic stress within tumors lead to exhaustion of melanoma antigen-specific CD8+ T cells
Cancer Immunology Research·2015
Recombinant Vaccine to HIV-1 Gag A Simian Replication-Defective Adenoviral
2013
Hexon-modified Recombinant E1-deleted Adenovirus Vectors as Dual Specificity Vaccine Carriers for Influenza Virus
Molecular Therapy·2012· 25 citedOpen Access
Highly Sensitive Method for Titration of Adenovirus Vectors v1
2011Open Access
Active Immunotherapy Combined With Blockade of a Coinhibitory Pathway Achieves Regression of Large Tumor Masses in Cancer-prone Mice
Molecular Therapy·2011· 48 citedOpen Access
Adeno-associated Virus Vectors Serotype 2 Induce Prolonged Proliferation of Capsid-Specific CD8+ T Cells in Mice
Molecular Therapy·2010· 28 citedOpen Access
Vaccine-induced T cells Provide Partial Protection Against High-dose Rectal SIVmac239 Challenge of Rhesus Macaques
Molecular Therapy·2010· 10 citedOpen Access
An efficient method of directly cloning chimpanzee adenovirus as a vaccine vector
Nature Protocols·2010· 63 citedOpen Access
Robust genital gag‐specific CD8<sup>+</sup> T‐cell responses in mice upon intramuscular immunization with simian adenoviral vectors expressing HIV‐1‐gag
European Journal of Immunology·2010· 14 citedOpen Access
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Frequent Co-authors

Hildegund C.J. Ertl(35), Zhiquan Xiang(18), Dongming Zhou(9), Anthony P Wlazlo(8), Marcio O. Lasaro(7), Mohadeseh Hasanpourghadi(7), Raj K. Kurupati(6), Xiang Zhou(6), Zhi Quan Xiang(6), Xiangyang Zhou(6), Dariusz Kowalczyk(5), Mikhail Novikov(5), Robert Ambrose(5), Arezki Chekaoui(5), Dakota Newman(5), Nia Tatsis(4), Ang Bian(4), Lauren J. DiMenna(4), Larissa H. Haut(4), Julie C. Fitzgerald(3)