Aram F. Hezel

University of Rochester Medical Center — United States

Medicine · Health Sciences

49h-index14.3kcitations218works10.82yr avg
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Research Topics

Pancreatic and Hepatic Oncology Research(67), Cholangiocarcinoma and Gallbladder Cancer Studies(54), Colorectal Cancer Treatments and Studies(38), Lung Cancer Treatments and Mutations(20), Hepatocellular Carcinoma Treatment and Prognosis(18)

Publications218 total

Supplementary Tables TS1 from Neoadjuvant Chemotherapy Is Associated with Altered Immune Cell Infiltration and an Anti-Tumorigenic Microenvironment in Resected Pancreatic Cancer
2025Open Access
Supplementary Figures FS1 from Neoadjuvant Chemotherapy Is Associated with Altered Immune Cell Infiltration and an Anti-Tumorigenic Microenvironment in Resected Pancreatic Cancer
2025Open Access
Supplementary Data from Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity
2025Open Access
Supplementary Data from Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity
2025Open Access
Abstract B075: Young- and older-onset pancreatic cancers arise through distinct mechanisms: Insights from genomic and germline analyses
Cancer Research·2025
Trial in progress: Phase 1 study of the selective protein degrader ASP4396 in patients with locally advanced or metastatic solid tumors with <i>KRAS G12D</i> mutations.
Journal of Clinical Oncology·2025· 1 cited
A Reassessment of the Clinical Utility of <sup>68</sup>Ga‐DOTATATE PET/CT in Patients With Gastroenteropancreatic Neuroendocrine Tumors
Journal of Surgical Oncology·2025Open Access
Neoadjuvant pemigatinib as a bridge to living donor liver transplantation for intrahepatic cholangiocarcinoma with FGFR2 gene rearrangement
American Journal of Transplantation·2024· 8 citedOpen Access
Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression
Nature Communications·2024· 42 citedOpen Access
425P Updated results of induction FOLFOX prior to CROSS chemoradiotherapy and surgery in patients with locally advanced esophageal and gastroesophageal junction cancer: A phase II study
Annals of Oncology·2024Open Access
<i>Smad4</i> restricts injury-provoked biliary proliferation and carcinogenesis
Disease Models & Mechanisms·2024· 9 citedOpen Access
SWI/SNF chromatin remodeling complex in pancreatic ductal adenocarcinoma: Clinicopathologic and immunohistochemical study
Human Pathology·2024· 5 cited
Total neoadjuvant therapy (TnT) with FOLFOX followed by short course radiation in locally advanced rectal cancer: A phase II study.
Journal of Clinical Oncology·2024
Abstract A035: Stromal composition, fibroblast heterogeneity and spatial organization in pancreatic adenocarcinoma
Cancer Research·2024
Organ Preservation and Survival by Clinical Response Grade in Patients With Rectal Cancer Treated With Total Neoadjuvant Therapy
JAMA Network Open·2024· 97 citedOpen Access
Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling
Cell Reports·2023· 26 citedOpen Access
Regorafenib in older adults with metastatic colorectal cancer: A multi-center, single arm phase II trial.
Journal of Clinical Oncology·2023· 1 cited
Abstract 1286: UNC5B promotes EMT and metastasis of pancreatic adenocarcinomas and expresses different isoforms that impact sensitivity to Netrin-1 blockade
Cancer Research·2023
Data from PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network
2023Open Access
Supplementary Table S6 from Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma
2023Open Access
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Frequent Co-authors

Nabeel Bardeesy(18), Ronald A. DePinho(11), Andrew X. Zhu(11), Richard F. Dunne(10), Charles S. Fuchs(9), Brian M. Wolpin(9), Vikram Deshpande(8), David C. Linehan(8), Andrew J. Aguirre(7), Jonathan A. Nowak(7), Daniel T. Chang(7), Albert C. Koong(7), Michael R. O’Dell(7), Gerald C. Chu(6), Lynda Chin(6), Douglas A. Rubinson(6), Lauren K. Brais(6), Chen Yuan(6), Thomas E. Clancy(6), Alec C. Kimmelman(5)