Shengna Han

Zhengzhou University — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index968citations59works2.72yr avg
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Research Topics

Cancer-related molecular mechanisms research(12), RNA modifications and cancer(12), Cardiac electrophysiology and arrhythmias(10), Ion channel regulation and function(7), Cancer-related gene regulation(7)

Publications59 total

HNF4A-AS1 promotes hepatic steatosis in metabolic dysfunction–associated steatotic liver disease by driving HNF4A degradation
Drug Metabolism and Disposition·2025
Lactylation in Cardiovascular Diseases: Current Progress and Perspectives
Journal of the American Heart Association·2025· 1 citedOpen Access
DSG3 promotes bladder cancer growth and metastasis via AKT/GSK3β/β-catenin pathway
Journal of Translational Medicine·2025· 1 citedOpen Access
METTL3 regulates rifampicin-induced CYP3A4 expression by activating PXR translation and nuclear import and stabilizing CYP3A4 mRNA
Biochemical Pharmacology·2025
Role of HNF4A-AS1/HNRNPC-mediated HNF4A ubiquitination protection against ritonavir-induced hepatotoxicity
Molecular Pharmacology·2025· 1 cited
List of contributors
Elsevier eBooks·2025
Epigenetics and pharmacoepigenetics of cardiovascular disorders
Elsevier eBooks·2025
Targeting the ALKBH5-NLRP3 positive feedback loop alleviates cardiomyocyte pyroptosis after myocardial infarction
European Journal of Pharmacology·2024· 5 cited
ALKBH5 promotes cardiac fibroblasts pyroptosis after myocardial infarction through Notch1/NLRP3 pathway
Cellular Signalling·2024· 3 cited
Epigenetic Regulation in Myocardial Fibroblasts and Its Impact on Cardiovascular Diseases
Pharmaceuticals·2024· 6 citedOpen Access
Methyltransferase Like-3–Mediated N6-Methyladenosine Modification of Long Noncoding RNA Hepatocyte Nuclear Factor 1a Antisense RNA 1/Hepatocyte Nuclear Factor 4a Antisense RNA 1 Regulates Cytochrome P450 Enzyme Expression
Drug Metabolism and Disposition·2024· 5 citedOpen Access
The long noncoding RNA HNF1A-AS1 with dual functions in the regulation of cytochrome P450 3A4
Biochemical Pharmacology·2024· 10 cited
ALKBH5 inhibitors as a potential treatment strategy in heart failure—inferences from gene expression profiling
Frontiers in Cardiovascular Medicine·2023· 8 citedOpen Access
An association study of HLA with levofloxacin-induced severe cutaneous adverse drug reactions in Han Chinese
iScience·2023· 7 citedOpen Access
HNF4A-AS1 Alleviates Ritonavir-induced Liver Injury via HNRNPC-mediated HNF4A Degradation
Journal of Pharmacology and Experimental Therapeutics·2023Open Access
Epigenetic Regulation of Macrophage Polarization in Cardiovascular Diseases
Pharmaceuticals·2023· 25 citedOpen Access
Prenatal Lipopolysaccharide Exposure Alters Hepatic Drug-Metabolizing Enzyme Expression in Mouse Offspring via Histone Modifications
Toxics·2023· 2 citedOpen Access
Ticagrelor reduces doxorubicin-induced pyroptosis of rat cardiomyocytes by targeting GSK-3β/caspase-1
Frontiers in Cardiovascular Medicine·2023· 8 citedOpen Access
The Long Noncoding Rna Hnf1a-As1 with Dual Functions in the Regulation of Cytochrome P450 3a4
SSRN Electronic Journal·2023Open Access
Comprehensive analysis of RNA m6A methylation in pressure overload-induced cardiac hypertrophy
BMC Genomics·2022· 13 citedOpen Access
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Frequent Co-authors

Lirong Zhang(36), Sumra Komal(12), Jianjian Yin(6), Liu-Gen Cui(6), Xue-Ling Su(6), Yi‐Ting Wang(6), Xiao‐bo Zhong(6), Shuhui Wang(5), Xiaofei Wang(5), Xinshou Ouyang(4), Chen‐Zheng Huang(4), Shitong Chen(4), Tianli Fan(4), Xuexiang Cha(4), Lina Xu(4), Pei Wang(4), Zhi‐Mo Wang(4), Yihang Yu(4), Yanyan Duan(3), Xiangjie Hu(3)