Michel L. Tremblay

McGill University Health Centre — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

78h-index21.7kcitations554works0.82yr avg
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Research Topics

Protein Tyrosine Phosphatases(290), Galectins and Cancer Biology(118), ATP Synthase and ATPases Research(105), Endoplasmic Reticulum Stress and Disease(77), RNA modifications and cancer(58)

Publications552 total

<i>Leishmania donovani</i>'s protein tyrosine phosphatases interact with <scp>DUF</scp>21 and respond to environmental magnesium
FEBS Journal·2025
Abstract A018: Targeting PTPN1/PTPN2 with KQ-791 enhances NK cell cytotoxicity during tumor rechallenge
Cancer Immunology Research·2025
Uncovering the individual immunotherapeutic roles of PTPN1 and PTPN2 in T cells during dual inhibition
iScience·2025· 1 citedOpen Access
The PTPN1 and PTPN2 phosphatases are Cooperative Regulators of Cancer Cell Immune Evasion
2025Open Access
<scp>PTPN2</scp> Negatively Regulates Macrophage Immune Responses and Cellular Bioenergetics
The FASEB Journal·2025· 2 citedOpen Access
Abstract 6940: Ptpn1 deficiency collaborates with a NUP98::HOXD13 fusion gene to generate B cell precursor acute lymphoblastic leukemia
Cancer Research·2025
Abstract 2166: PTPN1/2 dual inhibition sensitizes solid tumors to checkpoint blockade immunotherapy by enhancing T cell cytotoxicity and by decreasing cancer cell immune evasion
Cancer Research·2025
Supplementary Figure 1 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Table from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Figure 9 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Figure 8 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Figure 3 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Figure 2 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Figure 4 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Figure 6 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Figure 7 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Figure 11 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Figure 12 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Figure 10 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
Supplementary Figure 5 from PTP4A2 Promotes Glioblastoma Progression and Macrophage Polarization under Microenvironmental Pressure
2025Open Access
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Frequent Co-authors

Nadia Dubé(8), Alan Cheng(7), Noriko Uetani(6), Maxime Hallé(4), Matthew Stuible(4), Mounib Elchebly(3), Eva Michaliszyn(3), Brian P. Kennedy(3), Jacinthe Sirois(3), Silvia M. Vidal(3), Martin Olivier(3), Philippe Gros(3), Jean‐François Côté(3), Susan D. Spencer(3), Laurence A. Lasky(3), Mélanie J. Chagnon(3), Susan A. Gauthier(2), Paul D. Simoncic(2), Ailsa Lee-Loy(2), C. Jane McGlade(2)