Francisco Q. Gonçalves

University of Coimbra — Portugal

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index1.5kcitations31works0.02yr avg
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Research Topics

Adenosine and Purinergic Signaling(22), Neuroscience and Neuropharmacology Research(15), Neuroinflammation and Neurodegeneration Mechanisms(9), Vagus Nerve Stimulation Research(7), Nerve injury and regeneration(4)

Publications31 total

Adenosine A2A Receptors Shut Down Adenosine A1 Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term Potentiation
Biomolecules·2023· 12 citedOpen Access
Downregulation of Sirtuin 1 Does Not Account for the Impaired Long-Term Potentiation in the Prefrontal Cortex of Female APPswe/PS1dE9 Mice Modelling Alzheimer’s Disease
International Journal of Molecular Sciences·2023· 8 citedOpen Access
Feedback facilitation by adenosine A2A receptors of ATP release from mouse hippocampal nerve terminals
Purinergic Signalling·2023· 3 citedOpen Access
Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Adenosine in the Control of Behavioral and Electrophysiological Modifications Caused by Chronic Stress
ACS Chemical Neuroscience·2023· 17 citedOpen Access
Increased ATP Release and Higher Impact of Adenosine A2A Receptors on Corticostriatal Plasticity in a Rat Model of Presymptomatic Parkinson’s Disease
Molecular Neurobiology·2022· 23 citedOpen Access
CD73-Mediated Formation of Extracellular Adenosine Is Responsible for Adenosine A2A Receptor-Mediated Control of Fear Memory and Amygdala Plasticity
International Journal of Molecular Sciences·2022· 13 citedOpen Access
Adenosine A2A receptors control synaptic remodeling in the adult brain
Scientific Reports·2022· 20 citedOpen Access
Convergence of adenosine and GABA signaling for synapse stabilization during development
Science·2021· 76 citedOpen Access
Increased ATP release and CD73-mediated adenosine A2A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunction
Neurobiology of Disease·2021· 27 citedOpen Access
<scp>l</scp> ‐α‐aminoadipate causes astrocyte pathology with negative impact on mouse hippocampal synaptic plasticity and memory
The FASEB Journal·2021· 18 cited
Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slices
Scientific Reports·2021· 41 citedOpen Access
Clustering of adenosine A <sub>2B</sub> receptors with ectonucleotidases in caveolin‐rich lipid rafts underlies immunomodulation by <i>Leishmania amazonensis</i>
The FASEB Journal·2021· 7 cited
Crosstalk Between ATP-P2X7 and Adenosine A2A Receptors Controlling Neuroinflammation in Rats Subject to Repeated Restraint Stress
Frontiers in Cellular Neuroscience·2021· 36 citedOpen Access
Motor Deficits Coupled to Cerebellar and Striatal Alterations in Ube3am−/p+ Mice Modelling Angelman Syndrome Are Attenuated by Adenosine A2A Receptor Blockade
Molecular Neurobiology·2021· 11 cited
Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome
Neurobiology of Disease·2020· 12 citedOpen Access
Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine
Neurobiology of Disease·2019· 102 citedOpen Access
Enhanced ATP release and CD73‐mediated adenosine formation sustain adenosine A<sub>2A</sub> receptor over‐activation in a rat model of Parkinson's disease
British Journal of Pharmacology·2019· 48 citedOpen Access
Chronic adenosine A<sub>2A</sub> receptor blockade induces locomotor sensitization and potentiates striatal LTD IN GPR37‐deficient mice
Journal of Neurochemistry·2018· 11 citedOpen Access
Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions
eNeuro·2018· 76 citedOpen Access
Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease
Neurobiology of Disease·2018· 83 citedOpen Access
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Frequent Co-authors

Rodrigo A. Cunha(31), Ângelo R. Tomé(15), Paula M. Canas(13), Henrique B. Silva(12), Paula Agostinho(10), João Pedro Lopes(10), Daniel Rial(9), Nélio Gonçalves(8), Cristina Lemos(7), Joana I. Real(7), Ricardo J. Rodrigues(6), Samira G. Ferreira(5), Rui Daniel Prediger(4), Nuno J. Machado(4), Attila Köfalvi(4), António C. Silva(4), Ana Patrícia Simões(4), Joana M. Marques(4), Cátia R. Lopes(4), Geanne Matos de Andrade(3)