James E. Casanova

University of Virginia Health System — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

51h-index8.3kcitations140works1.52yr avg
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Research Topics

Cellular transport and secretion(49), Lipid Membrane Structure and Behavior(19), Cell Adhesion Molecules Research(14), Protein Kinase Regulation and GTPase Signaling(12), Erythrocyte Function and Pathophysiology(11)

Publications140 total

Loss of ARF5 impairs recovery after lysosomal damage
Frontiers in Molecular Biosciences·2025Open Access
<i>Salmonella</i>-induced cholesterol accumulation in infected macrophages suppresses autophagy via mTORC1 activation
Molecular Biology of the Cell·2024· 3 citedOpen Access
The mating pilus of <i>E. coli</i> pED208 acts as a conduit for ssDNA during horizontal gene transfer
mBio·2023· 17 citedOpen Access
Presentation of the AGA Distinguished Achievement Award in Basic Science to James R. Goldenring, MD, PhD, AGAF
Gastroenterology·2023Open Access
Phosphorylation of the inner core oligosaccharide of lipopolysaccharide mediates recognition and phagocytosis of Gram-negative bacteria by Brain Angiogenesis Inhibitor 1 (BAI1)
2023Open Access
Quantitation of RhoA activation: differential binding to downstream effectors
Small GTPases·2022· 5 citedOpen Access
The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and cilia to regulate ciliogenesis and ciliary protein traffic
Molecular Biology of the Cell·2022· 7 citedOpen Access
Quantitation of RhoA activation: differential binding to downstream effectors
Figshare·2022Open Access
The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and Cilia to Regulate Ciliogenesis and Ciliary Protein Traffic
2021· 4 citedOpen Access
Cover Image: <i>Salmonella</i> Typhimurium manipulates macrophage cholesterol homeostasis through the SseJ‐mediated suppression of the host cholesterol transport protein ABCA1 (Cellular Microbiology 08/2021)
Cellular Microbiology·2021· 1 cited
<i>Salmonella</i> Typhimurium manipulates macrophage cholesterol homeostasis through the <scp>SseJ</scp> ‐mediated suppression of the host cholesterol transport protein <scp>ABCA1</scp>
Cellular Microbiology·2021· 10 citedOpen Access
Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex
eLife·2020· 79 citedOpen Access
Author response: Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex
2020· 2 citedOpen Access
Non-redundant functions of FAK and Pyk2 in intestinal epithelial repair
Scientific Reports·2019· 15 citedOpen Access
A new Rab7 effector controls phosphoinositide conversion in endosome maturation
The Journal of Cell Biology·2017· 19 citedOpen Access
Bacterial Autophagy: Offense and Defense at the Host–Pathogen Interface
Cellular and Molecular Gastroenterology and Hepatology·2017· 57 citedOpen Access
The BRAG/IQSec family of Arf GEFs
Small GTPases·2016· 22 citedOpen Access
<i>Salmonella</i> Suppresses the TRIF-Dependent Type I Interferon Response in Macrophages
mBio·2016· 34 citedOpen Access
The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria
Science Signaling·2016· 70 citedOpen Access
<i>Science Signaling</i> Podcast for 2 February 2016: Engulf and Kill
Science Signaling·2016
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Frequent Co-authors

Ryan S. D’Souza(6), Steen H. Hansen(4), Lorraine C. Santy(4), Scott R. Frank(4), Katherine A. Owen(4), Dennis Brown(3), Delia J. Hernández-Deviez(3), Jean M. Wilson(3), Kim Ly(3), Kodi S. Ravichandran(3), Kathryn Conger(3), Massimo Sargiacomo(2), Michael P. Lisanti(2), Sylvain Bourgoin(2), Dennis A. Ausiello(2), Vladimir Marshansky(2), Xiaoye Wang(2), Ravindra Kumar(2), Jennifer Navarre(2), James R. Goldenring(2)