Dongwu Lai

Sir Run Run Shaw Hospital — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index990citations43works2.42yr avg
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Research Topics

Ion channel regulation and function(10), Cardiac electrophysiology and arrhythmias(9), Cardiomyopathy and Myosin Studies(6), Mitochondrial Function and Pathology(5), Cardiovascular Function and Risk Factors(4)

Publications42 total

Multi-omics analysis of early reperfused ischemic heart reveals ERRβ/γ activation protects against acute myocardial infarction injury
Journal of Advanced Research·2025Open Access
Determinants of mid-term response to left bundle branch pacing in heart failure patients with left bundle branch block
Canadian Journal of Cardiology·2025
Mitochondrial Tumor Suppressor 1A Attenuates Myocardial Infarction Injury by Maintaining the Coupling Between Mitochondria and Endoplasmic Reticulum
Circulation·2025· 10 cited
CEBPB drives a novel endothelial pathological phenotype and promotes atherosclerosis by directly upregulating TGFBR1 expression
Physiology·2025
Feasibility and safety of endomyocardial biopsy by lumenless pacing lead sheath–directed method during cardiac implantable electronic device implantation
Heart Rhythm·2024· 2 cited
Multi-omics map revealed PPAR <i>α</i> activation protecting against myocardial ischemia-reperfusion injury by maintaining cardiac metabolic homeostasis
2023Open Access
Endothelial FIS1 DeSUMOylation Protects Against Hypoxic Pulmonary Hypertension
Circulation Research·2023· 34 cited
Polydopamine (PDA) coatings with endothelial vascular growth factor (VEGF) immobilization inhibiting neointimal formation post zinc (Zn) wire implantation in rat aortas
Research Square (Research Square)·2023Open Access
Macrophage Dectin-1 mediates Ang II renal injury through neutrophil migration and TGF-β1 secretion
Cellular and Molecular Life Sciences·2023· 16 citedOpen Access
Polydopamine (PDA) coatings with endothelial vascular growth factor (VEGF) immobilization inhibiting neointimal formation post zinc (zn) wire implantation in rat aortas
Biomaterials Research·2023· 13 citedOpen Access
Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers
Proceedings of the National Academy of Sciences·2022· 51 citedOpen Access
Appraising the Causal Association between Systemic Iron Status and Heart Failure Risk: A Mendelian Randomisation Study
Nutrients·2022· 10 citedOpen Access
FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesis
Proceedings of the National Academy of Sciences·2022· 68 citedOpen Access
Predicting the Prognosis of Patients in the Coronary Care Unit: A Novel Multi-Category Machine Learning Model Using XGBoost
Frontiers in Cardiovascular Medicine·2022· 25 citedOpen Access
Exploring the Causal Effects of Circulating ST2 and Galectin-3 on Heart Failure Risk: A Mendelian Randomization Study
Frontiers in Cardiovascular Medicine·2022· 6 citedOpen Access
Ultrastructural and proteomic profiling of mitochondria-associated endoplasmic reticulum membranes reveal aging signatures in striated muscle
Cell Death and Disease·2022· 54 citedOpen Access
An Online Pre-procedural Nomogram for the Prediction of Contrast-Associated Acute Kidney Injury in Patients Undergoing Coronary Angiography
Frontiers in Medicine·2022· 9 citedOpen Access
Structural basis for the gating modulation of Kv4.3 by auxiliary subunits
Cell Research·2022· 20 citedOpen Access
Mean Scar Entropy by Late Gadolinium Enhancement Cardiac Magnetic Resonance Is Associated With Ventricular Arrhythmias Events in Hypertrophic Cardiomyopathy
Frontiers in Cardiovascular Medicine·2021· 19 citedOpen Access
Identification of Underlying Hub Genes Associated with Hypertrophic Cardiomyopathy by Integrated Bioinformatics Analysis
Pharmacogenomics and Personalized Medicine·2021· 12 citedOpen Access
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Frequent Co-authors

Guosheng Fu(23), Lenan Zhuang(8), Yingchao Gong(6), Yanggan Wang(6), Hong He(5), Lin Xu(5), Jun Cheng(5), Hyun Joung Lim(5), Ying Yang(5), Xizhi Wang(5), Wenbin Zhang(5), Luyang Yu(4), Zetao Ma(4), Xiaolu Shi(4), Shaoxiang Weng(4), Danfeng Zhong(4), Xingchen Wang(4), Jiangtao Guo(3), Cong Qiu(3), Yuan‐Qing Jiang(3)