Ilka Wittig

Goethe University Frankfurt — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

65h-index14.3kcitations315works3.82yr avg
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Research Topics

Mitochondrial Function and Pathology(122), ATP Synthase and ATPases Research(58), RNA modifications and cancer(34), Metabolism and Genetic Disorders(33), Cancer-related molecular mechanisms research(30)

Publications315 total

Lineage-restricted dependency on an oncofetal <i>SNHG29</i> -IGF2BP1 RNA axis in acute megakaryoblastic leukemia
2026Open Access
The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells
The EMBO Journal·2025Open Access
Modest improvement of metabolic and behavioral deficits with long-term ambroxol treatment in a Pink1−/−SNCAA53T double mutant mouse model of Parkinson’s disease
Acta Pharmacologica Sinica·2025Open Access
Persulfidation alters gene regulatory programs and promotes endothelial specification
Redox Biology·2025Open Access
Nuclear eNOS Interacts With and <i>S</i> -Nitrosates ADAR1 to Modulate Type I Interferon Signaling and Endothelial Function
Circulation·2025· 2 cited
<i>N</i> -glycans on SLC26A3 do not significantly alter plasma membrane or lipid raft trafficking, but appear to stabilize interdomain contacts to stimulate transport
American Journal of Physiology-Gastrointestinal and Liver Physiology·2025Open Access
QKI ensures splicing fidelity during cardiogenesis by engaging the U6 tri-snRNP to activate splicing at weak 5ʹ splice sites
2025Open Access
RTN4IP1 is required for the final stages of mitochondrial complex I assembly and CoQ biosynthesis
The EMBO Journal·2025Open Access
Microprotein SMIM26 drives oxidative metabolism via serine-responsive mitochondrial translation
Molecular Cell·2025· 5 cited
Rescuing Ischemic Brain Injury by Rewiring Mitochondrial Electron Flow
2025Open Access
Su1277: IDENTIFICATION OF DRA-INTERACTING PROTEINS IN ENDOCYTIC TRAFFICKING BY ULTRAID-TAG BASED PROXIMITY-DEPENDENT BIOTINYLATION
Gastroenterology·2025
Bi-allelic variants in MRPL49 cause variable clinical presentations, including sensorineural hearing loss, leukodystrophy, and ovarian insufficiency
The American Journal of Human Genetics·2025· 4 citedOpen Access
Formation of I2+III2 supercomplex rescues respiratory chain defects
Cell Metabolism·2025· 12 citedOpen Access
COA5 has an essential role in the early stage of mitochondrial complex IV assembly
Life Science Alliance·2025· 2 citedOpen Access
Long non-coding RNAs direct the SWI/SNF complex to cell type-specific enhancers
Nature Communications·2025· 15 citedOpen Access
N -glycans on SLC26A3 do not significantly alter plasma membrane or lipid raft trafficking, but appear to stabilize interdomain contacts to stimulate transport
JuSER Publikationsportal·2025Open Access
SLP2 and MIC13 synergistically coordinate MICOS assembly and crista junction formation
iScience·2024· 10 citedOpen Access
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy
Science·2024· 21 cited
Biallelic variants in <i>MRPL49</i> cause variable clinical presentations, including sensorineural hearing loss, leukodystrophy, and ovarian insufficiency
2024· 1 citedOpen Access
RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions
Communications Biology·2024· 4 citedOpen Access
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Frequent Co-authors

Hermann Schägger(14), Ulrich Brandt(13), Stefan Dröse(7), Andreas S. Reichert(6), Heinrich Heide(6), Michael Karas(5), Valentina Strecker(5), Holger Prokisch(5), Juliana Heidler(5), Lea Bleier(4), Mirco Steger(4), Tobias B. Haack(4), Thomas Meitinger(4), Jiong Hu(4), Ralf P. Brandes(4), Johannes A. Mayr(4), Tim M. Strom(4), Peter Freisinger(4), Birgit Haberberger(3), Boris Rolinski(3)