Giacomo Corleone

National Cancer Institute — Malaysia

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index2.5kcitations46works2.92yr avg
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Research Topics

Epigenetics and DNA Methylation(7), Single-cell and spatial transcriptomics(7), Genomics and Chromatin Dynamics(6), Cancer Genomics and Diagnostics(6), Multiple Myeloma Research and Treatments(5)

Publications46 total

Targeting of a novel interplay between MET tyrosine kinase and NRF2 enhances sensitivity to Paclitaxel in triple negative breast cancer
Journal of Experimental & Clinical Cancer Research·2026Open Access
Nuclear respiratory factor 1 promotes cell survival in multiple myeloma under proteasome inhibition therapy
Blood·2025· 1 citedOpen Access
p63 and ZNF148 cooperate to regulate head and neck squamous cell carcinoma
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
Targeting of a novel interplay between MET Tyrosine Kinase and NRF2 enhances sensitivity to Paclitaxel in Triple Negative Breast Cancer
2025Open Access
HBV-driven host chromatin accessibility changes affect liver metabolic pathways, iron homeostasis and promote a preneoplastic phenotype
Journal of Experimental & Clinical Cancer Research·2025· 2 citedOpen Access
WTAP and m6A-modified circRNAs modulation during stress response in acute myeloid leukemia progenitor cells
Cellular and Molecular Life Sciences·2024· 8 citedOpen Access
Che-1/miR-590-3p/TAZ axis sustains multiple myeloma disease
Leukemia·2024· 8 citedOpen Access
Deciphering Mutational Signature Dynamics in Hormone-Sensitive Breast Cancer During Treatment Adaptation.
Research Square (Research Square)·2023Open Access
hMENA isoforms regulate cancer intrinsic type I IFN signaling and extrinsic mechanisms of resistance to immune checkpoint blockade in NSCLC
Journal for ImmunoTherapy of Cancer·2023· 6 citedOpen Access
Che-1/miR-590-3p/TAZ axis sustains multiple myeloma disease.
2023Open Access
The long non-coding RNA NEAT1 is a ΔNp63 target gene modulating epidermal differentiation
Nature Communications·2023· 35 citedOpen Access
HBV infection reshapes host chromatin accessibility and affects choline and iron metabolism
Journal of Hepatology·2023
Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B
Nature Immunology·2022· 107 citedOpen Access
<scp>AATF</scp> /Che‐1 localizes to paraspeckles and suppresses R‐loops accumulation and interferon activation in Multiple Myeloma
The EMBO Journal·2022· 21 citedOpen Access
Enhancer plasticity sustains oncogenic transformation and progression of B-Cell Acute Lymphoblastic leukemia
2022
Dissecting the Epigenome Driving Drug Resistance by ATAC-Seq
Methods in molecular biology·2022· 3 cited
KEAP1 and TP53 Frame Genomic, Evolutionary, and Immunologic Subtypes of Lung Adenocarcinoma With Different Sensitivity to Immunotherapy
Journal of Thoracic Oncology·2021· 76 cited
AATF/Che-1, a new component of paraspeckles, controls R-loops formation and Interferon activation in Multiple Myeloma
2021Open Access
Che-1/AATF-induced transcriptionally active chromatin promotes cell proliferation in multiple myeloma
Blood Advances·2020· 13 citedOpen Access
KEAP1-driven co-mutations in lung adenocarcinoma unresponsive to immunotherapy despite high tumor mutational burden
Annals of Oncology·2020· 218 citedOpen Access
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Frequent Co-authors

Francesca De Nicola(18), Maurizio Fanciulli(16), Luca Magnani(15), Giancarlo Pruneri(10), Iros Barozzi(7), R. Charles Coombes(7), Tiziana Bruno(7), Clelia Cortile(7), Frauke Goeman(6), Valeria Catena(6), Svitlana Gumenyuk(6), Johannes Köster(5), Davis J. McCarthy(5), Stephanie C. Hicks(5), Mark D. Robinson(5), Catalina A. Vallejos(5), Kieran R. Campbell(5), Niko Beerenwinkel(5), Ahmed Mahfouz(5), Luca Pinello(5)