Bhuvaneshwari Mahalingam

Harvard University — United States

Immunology and Microbiology · Life Sciences

9h-index1.1kcitations10works0.02yr avg
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Research Topics

HIV Research and Treatment(5), HIV/AIDS drug development and treatment(5), Cell Adhesion Molecules Research(4), HIV/AIDS Research and Interventions(2), Monoclonal and Polyclonal Antibodies Research(2)

Publications10 total

Atomic Basis for the Species-specific Inhibition of αV Integrins by Monoclonal Antibody 17E6 Is Revealed by the Crystal Structure of αVβ3 Ectodomain-17E6 Fab Complex
Journal of Biological Chemistry·2014· 30 citedOpen Access
AlphaVBeta3 integrin in complex with monoclonal antibody FAB fragment.
2013· 3 cited
Stable Coordination of the Inhibitory Ca2+ Ion at the Metal Ion-Dependent Adhesion Site in Integrin CD11b/CD18 by an Antibody-Derived Ligand Aspartate: Implications for Integrin Regulation and Structure-Based Drug Design
The Journal of Immunology·2011· 32 citedOpen Access
INTEGRIN STRUCTURE, ALLOSTERY, AND BIDIRECTIONAL SIGNALING
Annual Review of Cell and Developmental Biology·2005· 543 cited
Crystal structures of HIV protease V82A and L90M mutants reveal changes in the indinavir‐binding site
European Journal of Biochemistry·2004· 80 citedOpen Access
Effect of sequence polymorphism and drug resistance on two HIV‐1 Gag processing sites
European Journal of Biochemistry·2002· 75 citedOpen Access
Combining mutations in HIV‐1 protease to understand mechanisms of resistance
Proteins Structure Function and Bioinformatics·2002· 47 cited
Structural implications of drug‐resistant mutants of HIV‐1 protease: High‐resolution crystal structures of the mutant protease/substrate analogue complexes
Proteins Structure Function and Bioinformatics·2001· 132 cited
Structural model of human glucokinase in complex with glucose and ATP: implications for the mutants that cause hypo- and hyperglycemia.
Diabetes·1999· 76 cited
Structural and kinetic analysis of drug resistant mutants of HIV‐1 protease
European Journal of Biochemistry·1999· 132 cited

Frequent Co-authors

Robert W. Harrison(6), Irene T. Weber(6), John M. Louis(5), Jian-Ping Xiong(4), M. Amin Arnaout(3), Yuan‐Fang Wang(3), Péter Boross(3), József Tőzsér(3), José Luís Izquierdo Alonso(3), Saurabh Anand(2), Brian D. Adair(2), Johannes F. Van Agthoven(2), Jason Hung(1), Charles C. Reed(1), Jill M. Adomat(1), Jennifer Krouse(1), Antonio L. Cuesta‐Muñoz(1), Elizabeth A. Davis(1), Franz M. Matschinsky(1), Anita Fehér(1)