David M. Margolis

University of North Carolina at Chapel Hill — United States

Immunology and Microbiology · Life Sciences

86h-index29.9kcitations594works1.72yr avg
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Research Topics

HIV Research and Treatment(387), HIV/AIDS drug development and treatment(233), HIV/AIDS Research and Interventions(182), Immune Cell Function and Interaction(104), HIV-related health complications and treatments(54)

Publications588 total

Single-cell characterization of the gastrointestinal HIV reservoir reveals heterogeneous cellular phenotypes
Journal of Clinical Investigation·2025Open Access
The role of Vpr in a primary CD4+ T-cell model of HIV-1 latency 3672
The Journal of Immunology·2025Open Access
HIV-1 accessory protein Vpr possesses a cryptic p300-dependent transcription-promoting activity that is blocked by histone deacetylases in CD4+ T cells
UNC Libraries·2025Open Access
The persistent pool of HIV-1-infected cells is formed episodically during untreated infection.
UNC Libraries·2025Open Access
Efficacy, pharmacokinetics and neurocognitive performance of dual, NRTI-sparing antiretroviral therapy in acute HIV-infection.
UNC Libraries·2025Open Access
Longitudinal Dynamics of Intact HIV Proviral DNA and Outgrowth Virus Frequencies in a Cohort of Individuals Receiving Antiretroviral Therapy
UNC Libraries·2025Open Access
Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy
UNC Libraries·2025Open Access
Stable Latent HIV Infection and Low-level Viremia Despite Treatment With the Broadly Neutralizing Antibody VRC07-523LS and the Latency Reversal Agent Vorinostat
UNC Libraries·2025Open Access
HIV post-treatment controllers have distinct immunological and virological features
UNC Libraries·2025Open Access
The role of Tat in HIV latency and reactivation
UNC Libraries·2025Open Access
HIV-1 accessory protein Vpr possesses a cryptic p300-dependent transcription-promoting activity that is blocked by histone deacetylases in CD4+ T cells
PLoS Pathogens·2025Open Access
The role of Tat in HIV latency and reactivation
Frontiers in Immunology·2025· 4 citedOpen Access
Persistent type I interferon signaling within the brain of people with HIV on ART with cognitive impairment
PLoS Pathogens·2025· 4 citedOpen Access
Silk fibers assisted long-term 3D culture of human primary urinary stem cells via inhibition of senescence-associated genes: Potential use in the assessment of chronic mitochondrial toxicity
UNC Libraries·2025Open Access
Dominant CD4+ T cell receptors remain stable throughout antiretroviral therapy-mediated immune restoration in people with HIV
UNC Libraries·2025Open Access
The histone methyltransferase SETD2 regulates HIV expression and latency
UNC Libraries·2025Open Access
Correction for Raines et al., “Nanoparticle delivery of Tat synergizes with classical latency reversal agents to express HIV antigen targets”
Antimicrobial Agents and Chemotherapy·2025Open Access
Correction for Garrido et al., “Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal Ex Vivo”
UNC Libraries·2025Open Access
Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
UNC Libraries·2025Open Access
Single cell analysis of HIV expression and integration sites reveals robust viral expression across diverse chromatin environments
2025· 1 citedOpen Access
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Frequent Co-authors

Nancie M. Archin(17), Joseph J. Eron(11), Ronald J. Bosch(9), Daria J. Hazuda(7), John M. Coffin(6), Douglas D. Richman(5), Myron S. Cohen(5), J. Víctor García(5), Angela D. M. Kashuba(4), Mary F. Kearney(4), John W. Mellors(4), Cynthia L. Gay(4), Jeffrey D. Lifson(4), Mark C. Walters(4), Amy S. Espeseth(4), Angela Wahl(4), Yixuan J. Hou(3), Caitlin E. Edwards(3), Longping V. Tse(3), Alena J. Markmann(3)