Ellen Skarpen

Oslo University Hospital — Norway

Medicine · Health Sciences

22h-index1.4kcitations62works0.02yr avg
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Research Topics

Cancer-related Molecular Pathways(10), Liver physiology and pathology(9), Hemophilia Treatment and Research(8), Photodynamic Therapy Research Studies(7), Protein Kinase Regulation and GTPase Signaling(6)

Publications62 total

Light-enhanced cytotoxicity and intracellular trafficking of the PD-L1-targeting photoimmunoconjugate EITC-atezolizumab
Biomedicine & Pharmacotherapy·2025Open Access
Identification and evaluation of Pharmacological enhancers of the factor VII p.Q160R variant
Scientific Reports·2025Open Access
Developmental neurotoxicity of acrylamide and its metabolite glycidamide in a human mixed culture of neurons and astrocytes undergoing differentiation in concentrations relevant for human exposure
NeuroToxicology·2022· 14 citedOpen Access
The Factor VII Variant p.A354V-p.P464Hfs: Clinical versus Intracellular and Biochemical Phenotypes Induced by Chemical Chaperones
Applied Sciences·2021· 1 citedOpen Access
Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
Thrombosis and Haemostasis·2021· 1 cited
Molecular Characterization of Two Homozygous Factor VII Variants Associated with Intracranial Bleeding
Blood·2020
Characterizing Coagulation FVII from iPSC-Hepatocytes-like Cells: Setting the Basis for Cell Therapy Development
Blood·2020
Predictive biomarkers for <scp>5‐ALA‐PDT</scp> can lead to personalized treatments and overcome tumor‐specific resistances
Cancer Reports·2020· 20 citedOpen Access
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
Nature Cell Biology·2020· 131 citedOpen Access
Photodynamic Efficacy of Cercosporin in 3D Tumor Cell Cultures
Photochemistry and Photobiology·2020· 14 citedOpen Access
The effect of the chemical chaperone 4-phenylbutyrate on secretion and activity of the p.Q160R missense variant of coagulation factor FVII
Cell & Bioscience·2019· 15 citedOpen Access
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
Nature Communications·2019· 126 citedOpen Access
Unrestrained ESCRT-III drives chromosome fragmentation and micronuclear catastrophe
2019· 12 citedOpen Access
The Chemical Chaperone 4-Phenylbutyrate Increases Secretion and Activity of Missense and Elongated Factor VII Mutants
Blood·2018
Light-enhanced VEGF121/rGel: A tumor targeted modality with vascular and immune-mediated efficacy
Journal of Controlled Release·2018· 22 cited
Modulation of Secretory Lysosomes During NK Cell Education Leads to Accumulation of Granzyme B and Enhanced Functional Potential
2018· 4 citedOpen Access
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency
Thrombosis and Haemostasis·2018· 8 citedOpen Access
Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins
Photochemical & Photobiological Sciences·2018· 29 citedOpen Access
The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology
Biological Research·2018· 29 citedOpen Access
Factor VII deficiency: Unveiling the cellular and molecular mechanisms underlying three model alterations of the enzyme catalytic domain
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2017· 16 citedOpen Access
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Frequent Co-authors

Henrik S. Huitfeldt(24), Morten P. Oksvold(14), Kristian Berg(11), Birgitte Lindeman(9), Lene Wierød(8), Carola M. Rosseland(7), Andreas Brech(6), Harald Stenmark(6), María Eugenia Chollet(6), Theodossis A. Theodossiou(5), Elisabeth Andersen(5), Per Morten Sandset(5), Grethe Skretting(5), Anders Høgset(4), Pål Kristian Selbo(4), Liv Ingrid Flinder(4), Anette Weyergang(4), Michael G. Rosenblum(4), H. Grøsvik(4), E. Vibeke Thrane(4)