Eileen M. Kasperek

University at Buffalo, State University of New York — United States

Medicine · Health Sciences

16h-index1.5kcitations41works0.82yr avg
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Research Topics

Salivary Gland Disorders and Functions(12), Ion channel regulation and function(9), Ubiquitin and proteasome pathways(8), Neuroscience and Neuropharmacology Research(7), Retinal Development and Disorders(7)

Publications41 total

IL-36 mediates immune activation in Sjögren's disease and may represent a novel biomarker of disease
Journal of Leukocyte Biology·2025Open Access
Tlr9 governs Tlr7-mediated disease in a mouse model of primary Sjogren’s disease in a sex-biased manner 3918
The Journal of Immunology·2025Open Access
Tlr9 expression protects against Tlr7-dependent exocrine gland and systemic disease manifestations in primary Sjögren's disease in a sex-biased manner
Journal of Autoimmunity·2025· 1 citedOpen Access
Tlr7 drives sex- and tissue-dependent effects in Sjögren’s disease
Frontiers in Cell and Developmental Biology·2024· 2 citedOpen Access
TLR7 activation of age-associated B cells mediates disease in a mouse model of primary Sjögren's disease
Journal of Leukocyte Biology·2023· 15 citedOpen Access
TLR7 expression increases with disease progression and mediates expansion of distinct B cell subsets in primary Sjögren’s Disease
The Journal of Immunology·2023Open Access
TLR7 agonism accelerates disease in a mouse model of primary Sjögren’s syndrome and drives expansion of T-bet+ B cells
Frontiers in Immunology·2022· 14 citedOpen Access
The TLR7 agonist imiquimod mediates immune activation in primary Sjögren’s syndrome
The Journal of Immunology·2022
Immune-Intrinsic Myd88 Directs the Production of Antibodies With Specificity for Extracellular Matrix Components in Primary Sjögren’s Syndrome
Frontiers in Immunology·2021· 15 citedOpen Access
Myd88 activation in immune cells governs distinct disease manifestations in primary Sjögren’s syndrome
The Journal of Immunology·2021
Tissue-specific activation of Myd88-dependent pathways governs disease severity in primary Sjögren's syndrome
Journal of Autoimmunity·2021· 14 citedOpen Access
Contributions by N-terminal Domains to NMDA Receptor Currents
2020· 7 citedOpen Access
Activation of Myd88-Dependent TLRs Mediates Local and Systemic Inflammation in a Mouse Model of Primary Sjögren's Syndrome
Frontiers in Immunology·2020· 48 citedOpen Access
Multiple Myd88-dependent Toll-like receptor signaling pathways mediate inflammation in a mouse model of primary Sjögren’s syndrome
The Journal of Immunology·2019
receptorsreaction mechanism of neuronal NMDA
2015
Separate Intramolecular Targets for Protein Kinase A Control N-Methyl-d-aspartate Receptor Gating and Ca2+ Permeability
Journal of Biological Chemistry·2014· 37 citedOpen Access
Gating reaction mechanism of neuronal NMDA receptors
Journal of Neurophysiology·2012· 28 citedOpen Access
Probing the activation sequence of NMDA receptors with lurcher mutations
The Journal of General Physiology·2012· 36 citedOpen Access
NMDA receptor activation requires remodelling of intersubunit contacts within ligand-binding heterodimers
Nature Communications·2011· 40 citedOpen Access
Activation Mechanism of Native NMDA Receptors in Cultured Rat Neurons in Culture
Biophysical Journal·2009Open Access
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Frequent Co-authors

Jill M. Kramer(13), Cecile M. Pickart(8), Shahrokh C. Khani(7), Jeremy Kiripolsky(7), Gabriela Popescu(7), Chengsong Zhu(7), Yu Guan(6), Achamaporn Punnanitinont(6), Bruce J. Nicholson(5), I. Martha Skerrett(4), William F. Borschel(4), Jason Myers(4), Jeffrey C. Miecznikowski(4), Rose‐Anne Romano(3), Quan‐Zhen Li(3), Jia Wang(3), Sheta Biswas(3), Jin Young(3), Basil S. Pawlyk(2), Oleg V. Bulgakov(2)