Yukio Hitotsuyanagi

Tokyo University of Pharmacy and Life Sciences — Japan

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

30h-index2.9kcitations239works0.92yr avg
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Research Topics

Pharmacological Effects of Natural Compounds(33), Morinda citrifolia extract uses(32), Phytochemical compounds biological activities(28), Natural product bioactivities and synthesis(24), Crystallization and Solubility Studies(24)

Publications239 total

Structures of bicyclic hexapeptides RA-XXXIII—RA-XXXIX and cyclic peptides cyclorubipeptides B and C from Rubia cordifolia
Tetrahedron·2026
Synthesis of pisiferic acid analogues and their anti-adipogenic effect in 3T3-L1 adipocytes
Bioorganic & Medicinal Chemistry Letters·2025
Structures of neo-RA-VII and cyclorubipeptide A, new cyclic hexapeptides from Rubia cordifolia
Tetrahedron·2025· 1 cited
Synthesis and cytotoxicity evaluation of tyrosine-3 or tyrosine-6 fluorinated analogues of RA-VII, an antitumor bicyclic hexapeptide from Rubia cordifolia
Phytochemistry Letters·2025
Structures of new cytotoxic bicyclic hexapeptides with a phenylpropanoid unit from Rubia cordifolia
Phytochemistry Letters·2024· 2 cited
Synthesis of Antitumor Bicyclic Hexapeptide RA-VII Analogues Possessing an Aromatic Amino Acid at Residue 2
The Journal of Organic Chemistry·2024· 1 cited
Structures of bicyclic hexapeptides RA-XXVII and RA-XXVIII from Rubia cordifolia L.
Tetrahedron Letters·2024· 4 cited
Syntheses and Structure–Activity Relationship Studies of Antitumor Bicyclic Hexapeptide RA-VII Analogues
YAKUGAKU ZASSHI·2024· 1 citedOpen Access
Synthesis of carbacycloisodityrosine, an analogue of cycloisodityrosine in antitumor bicyclic hexapeptide RA-VII
Tetrahedron Letters·2024
Kamebakaurin Suppresses Antigen-Induced Mast Cell Activation by Inhibition of FcεRI Signaling Pathway
International Archives of Allergy and Immunology·2024
CCDC 2260138: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
CCDC 2259955: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Synthesis and cytotoxicity evaluation of retro-inverso analogue of antitumor bicyclic hexapeptide RA-VII
Tetrahedron Letters·2023· 4 cited
Difluoromethoxy and fluoromethoxy analogues of antitumor bicyclic peptide RA-VII
Phytochemistry Letters·2023· 2 cited
Synthesis and Cytotoxicity Evaluation of Tyrosine-5 Fluorinated Analogues of RA-VII, An Antitumor Bicyclic Hexapeptide
Synlett·2023· 5 cited
CCDC 2206162: Experimental Crystal Structure Determination
The Cambridge Structural Database·2023Open Access
Synthesis of 1-O-acyl- and 1-oxo-kamebanin analogues and their cytotoxic activity
Bioorganic & Medicinal Chemistry Letters·2023
Synthesis of Protected L,L-Cyclotryptophyltyrosine, a Key Unit of Tryptorubin A
Heterocycles·2023Open Access
Synthesis and Cytotoxicity Evaluation of Retro-Inverso Analog of Antitumor Bicyclic Hexapeptide Ra-Vii
SSRN Electronic Journal·2023Open Access
Synthesis and cytotoxicity evaluation of fluorinated brusatol, bruceosin, and dehydrobrusatol
Results in Chemistry·2023Open Access
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Frequent Co-authors

Koichi Takeya(22), Koichi Takeya(21), Hideji Itokawa(15), Haruhiko Fukaya(14), Tomoyo Hasuda(9), Shin‐ichiro Sakai(5), Norio Aimi(5), Koichi Shudo(5), Yutaka Aoyagi(5), Ichiro Takano(5), Ichiro Yasuda(5), Motohiro NISHIJIMA(5), Yasuyuki Endo(4), Kazuyuki Kondo(4), Kumiko Mitsui(4), M. Kobayashi(3), Akiko Itai(3), Yasumasa Koyama(3), Ik Hwi Kim(3), Masumi Villeneuve(3)