Thomas C. Nugent

Constructor University — Germany

Chemistry · Physical Sciences

19h-index2.0kcitations60works0.02yr avg
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Research Topics

Asymmetric Synthesis and Catalysis(28), Asymmetric Hydrogenation and Catalysis(27), Chemical Synthesis and Analysis(16), Synthetic Organic Chemistry Methods(8), Chemical Synthesis and Reactions(8)

Publications60 total

Defining Aldol Chemoselectivity in the Presence of Henry Nucleophiles (Nitroalkanes)
Molecules·2025Open Access
Aromatic Functionalized Indanones and Indanols: Broad Spectrum Intermediates for Drug Candidate Diversification
Organics·2024Open Access
Enantioselective Catalytic Aldol Reactions in the Presence of Knoevenagel Nucleophiles: A Chemoselective Switch Optimized in Deep Eutectic Solvents Using Mechanochemistry
Molecules·2023· 2 citedOpen Access
Supramolecular Catalysis of a Catalysis-Resistant Diels–Alder Reaction: Almost Theoretical Acceleration of Cyclopentadiene Dimerization inside Cucurbit[7]uril
ACS Catalysis·2022· 41 cited
A 2000 to 2020 Practitioner's Guide to Chiral Amine‐Based Enantioselective Aldol Reactions: Ketone Substrates, Best Methods, in Water Reaction Environments, and Defining Nuances.
European Journal of Organic Chemistry·2021· 12 cited
Supramolecular Catalysis of a Catalysis-Resistant Diels-Alder Reaction: Rapid Dimerization of Cyclopentadiene inside Cucurbit[7]uril
2021· 1 citedOpen Access
Supramolecular Catalysis of a Catalysis-Resistant Diels-Alder Reaction: Rapid Dimerization of Cyclopentadiene inside Cucurbit[7]uril
2021Open Access
Harnessing Additional Capability from in Water Reaction Conditions: Aldol <i>versus</i> Knoevenagel Chemoselectivity
Advanced Synthesis & Catalysis·2021· 8 citedOpen Access
Catalytic Access to Succinimide Products Containing Stereogenic Quaternary Carbons
ChemistrySelect·2020· 30 citedOpen Access
Carboxylate Salt Bridge‐Mediated Enamine Catalysis: Expanded Michael Reaction Substrate Scope and Facile Access to Antidepressant (<i>R</i>)‐Pristiq
Advanced Synthesis & Catalysis·2017· 13 cited
A Catalyst‐Directed Remote Stereogenic Center Switch During the Site‐Selective Aldol Desymmetrization of Cyclohexanone‐Based Diketones
Advanced Synthesis & Catalysis·2016· 8 cited
Beyond Chemoselectivity: Catalytic Site‐Selective Aldolization of Diketones and Exploitation for Enantioselective Alzheimer's Drug Candidate Synthesis
Chemistry - A European Journal·2016· 13 cited
CCDC 1427190: Experimental Crystal Structure Determination
The Cambridge Structural Database·2016Open Access
An investigation of the observed, but counter-intuitive, stereoselectivity noted during chiral amine synthesis via <i>N</i>-chiral-ketimines
Beilstein Journal of Organic Chemistry·2013· 1 citedOpen Access
ChemInform Abstract: Chiral Picolylamines for Michael and Aldol Reactions: Probing Substrate Boundaries.
ChemInform·2013· 1 cited
Step-Efficient Access to Chiral Primary Amines
Synthesis·2013· 18 cited
Noncovalent Bifunctional Organocatalysts: Powerful Tools for Contiguous Quaternary‐Tertiary Stereogenic Carbon Formation, Scope, and Origin of Enantioselectivity
Chemistry - A European Journal·2012· 90 cited
Chiral picolylamines for Michael and aldol reactions: probing substrate boundaries
Organic & Biomolecular Chemistry·2012· 36 cited
CCDC 840712: Experimental Crystal Structure Determination
The Cambridge Structural Database·2012Open Access
ChemInform Abstract: Sequential Reductive Amination—Hydrogenolysis: A One‐Pot Synthesis of Challenging Chiral Primary Amines.
ChemInform·2011
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Frequent Co-authors

Mohamed El‐Shazly(7), Tomáš Hudlický(6), Abdul Sadiq(6), Ahtaram Bibi(6), Vijay N. Wakchaure(6), Muhammad Umar(5), Foad N. Tehrani(5), Hussein Ali El Damrany Hussein(5), Ishtiaq Hussain(5), Sophie Bergeron(4), Michael W. Cappi(4), Stanley M. Roberts(4), Abhijit Ghosh(4), Rashmi Ranjan Mohanty(4), Muhammad Harris Shoaib(4), Khaleel I. Assaf(3), Robert Hein(3), Werner M. Nau(3), Foad Tehrani Najafian(3), Brian M. Adger(2)