N Kurata

Showa University — Japan

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

8h-index228citations23works3.02yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(8), Metabolism and Genetic Disorders(4), Alcohol Consumption and Health Effects(4), Eicosanoids and Hypertension Pharmacology(4), Drug Transport and Resistance Mechanisms(3)

Publications23 total

Comparative Analysis of Verapamil Pharmacokinetics: Evaluating the Impact of Simple Suspension and Crushing Administration Methods
Journal of Clinical Medicine·2024· 3 citedOpen Access
Long-term use of late evening snack with branched chain amino acids improve fisher ratio in patients with liver cirrhosis
Clinical Nutrition·2018
PT02.4: Late Evening Snack with Branched Chain Amino Acid Improves Fischer Ratio at Fasting, in the Next Morning
Clinical Nutrition·2017
Evaluation of the effects of hydrophilic organic solvents on CYP3A-mediated drug-drug interaction<i>in vitro</i>
Human & Experimental Toxicology·2006· 29 cited
Involvement of cytochrome P450 2C9, 2E1 and 3A4 in trimethadione N-demethylation in human microsomes
Journal of Clinical Pharmacy and Therapeutics·2003· 6 citedOpen Access
How useful is the ‘cocktail approach’ for evaluating human hepatic drug metabolizing capacity using cytochrome P450 phenotyping probes <i>in vivo</i>?
Journal of Clinical Pharmacy and Therapeutics·2003· 76 citedOpen Access
Effects of imidazole antimycotics on the liver microsomal cytochrome P450 isoforms in rats: comparison ofin vitro andex vivo studies
European Journal of Drug Metabolism and Pharmacokinetics·2000· 28 cited
Mechanism of alteration of the hepatic and small intestinal drug metabolizing enzymes in adenine-induced renal failure in rats
1999
Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1
Xenobiotica·1998· 19 cited
Trimethadione N-demethylation by rat liver CYP2E1 in vitro.
PubMed·1996· 2 cited
Pharmacokinetic study of trimethadione and its metabolite in blood, liver and brain by microdialysis in conscious, unrestrained rats.
PubMed·1995· 10 cited
[Application of microdialysis for pharmacokinetic study in rabbit anterior chamber].
PubMed·1995· 3 cited
The effects of inhibitors and substrates of different types of cytochrome P450 isozymes on serum dimethadione/trimethadione ratio in rats in vivo.
PubMed·1995· 1 cited
Antipyrine concentrations in liver and blood monitored by microdialysis of unrestrained conscious rats.
PubMed·1993· 10 cited
The effects of ebselen on hepatic microsomal monoxygenase system in rats
Asia Pacific journal of pharmacology·1992· 2 cited
Studies on inhibition and induction of metabolism of ethyl carbamate by acetone and related compounds. Evidence for metabolism by cytochromes P-450.
Drug Metabolism and Disposition·1991· 14 cited
Studies on induction of metabolism of ethyl carbamate in mice by ethanol.
Drug Metabolism and Disposition·1991· 8 cited
Inhibition of the metabolism of ethyl carbamate by acetaldehyde.
Drug Metabolism and Disposition·1990· 10 cited
Studies on induction of metabolism of ethyl carbamate (EC) in mice by ethanol
FASEB Journal (Federation of American Societies for Experimental Biology); (United States)·1990
Long-term effects of phenobarbital on rat liver microsomal drug-metabolizing enzymes and heme-metabolizing enzyme.
PubMed·1989· 7 cited
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Frequent Co-authors

Hideaki Yasuhara(8), Yuki Nishimura(4), Harrell E. Hurst(4), Raymond A. Kemper(4), William J. Waddell(4), E. Uchida(4), Satoshi Kobayashi(3), Einosuke Tanaka(2), Masayasu Iwase(2), Masatoshi Inagaki(2), Y Nishimura(2), K. Oguchi(2), E Uchida(2), Naoki Uchida(2), Hiroshi Yasuhara(2), Hiroki Maki(2), Hisami Yamanaka‐Okumura(2), A. Hosoda(2), Fumitake Amemiya(2), H Toribe(2)