Hiu‐Chi Chong

Hong Kong Polytechnic University — Hong Kong

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index552citations9works0.02yr avg
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Research Topics

Cancer Research and Treatments(7), Virus-based gene therapy research(6), Polyamine Metabolism and Applications(3), Nanoplatforms for cancer theranostics(2), Peptidase Inhibition and Analysis(2)

Publications9 total

Arginine Is a Novel Drug Target for Arginine Decarboxylase in Human Colorectal Cancer Cells
International Journal of Molecular Sciences·2023· 12 citedOpen Access
Mono-PEGylated thermostable Bacillus caldovelox arginase mutant (BCA-M-PEG20) induces apoptosis, autophagy, cell cycle arrest and growth inhibition in gastric cancer cells
Investigational New Drugs·2022· 4 citedOpen Access
Mono-PEGylated Thermostable Bacillus caldovelox Arginase Mutant (BCA-M-PEG20) Induces Apoptosis, Autophagy, Cell Cycle Arrest and Growth Inhibition on Gastric Cancer Cells
Research Square (Research Square)·2022Open Access
Modification of N-Terminal α-Amino Groups of Peptides and Proteins Using Ketenes
Journal of the American Chemical Society·2012· 163 cited
Immobilization of engineered arginase on gold-carbon nanotubes
Chemical Communications·2012· 7 cited
Recombinant human arginase inhibits the in vitro and in vivo proliferation of human melanoma by inducing cell cycle arrest and apoptosis
Pigment Cell & Melanoma Research·2010· 100 cited
A Highly Selective FRET‐Based Fluorescent Probe for Detection of Cysteine and Homocysteine
Chemistry - A European Journal·2010· 108 cited
Pegylated derivatives of recombinant human arginase (rhArg1) for sustained in vivo activity in cancer therapy: preparation, characterization and analysis of their pharmacodynamics in vivo and in vitro and action upon hepatocellular carcinoma cell (HCC)
Cancer Cell International·2009· 72 citedOpen Access
Recombinant human arginase inhibits proliferation of human hepatocellular carcinoma by inducing cell cycle arrest
Cancer Letters·2009· 86 cited

Frequent Co-authors

Yun‐Chung Leung(9), Alan Tin‐Lun Lam(3), Paul N. Cheng(3), Denys N. Wheatley(3), Wai‐Hung Lo(3), Sui-Yi Kwok(3), Leo Man-Yuen Lee(3), Man‐Kin Wong(2), Chi‐Ming Che(2), Gabriel Wong(2), Ho‐Yin Chow(2), T.L. Chow(2), Sai‐Fung Chung(2), Suet-Ying Tam(2), Chi-Fai Kim(2), Anna On‐Yee Chan(1), Chi‐Ming Ho(1), Jie‐Sheng Huang(1), Hoi‐Yan Shiu(1), Sui‐Yi Kwok(1)