Adak Karamafrooz

Lambda Instruments (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

5h-index141citations17works0.02yr avg
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Research Topics

Protein Structure and Dynamics(5), Enzyme Structure and Function(4), Monoclonal and Polyclonal Antibodies Research(3), Hormonal Regulation and Hypertension(3), Cancer Research and Treatments(3)

Publications17 total

A noninvasive urine biomarker CXCL10 bead-based detection assay for monitoring renal transplants
Human Immunology·2025
Interrogation of Interfering Factors in <scp>ELISA</scp> Detecting Angiotensin Receptor Antibodies and Specificity Validation Using the Adsorption Elution Crossmatch (<scp>AXE</scp>) Technique
HLA·2025Open Access
Comparison of two Elisa-based Angiotensin II-type-1 receptor (AT1R) autoantibody detection assays using an antibody cross-reactivity check approach
Human Immunology·2024
P519 Deciphering the loss of anti-angiotensin type 1 receptor reactivity in enzyme-linked immunosorbent assay post-adsorption
Human Immunology·2023· 1 cited
Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination
Cell Reports·2023· 7 citedOpen Access
Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination
2023Open Access
Integrated Phosphoproteomics for Identifying Substrates of Human Protein Kinase A (<i>PRKACA</i>) and Its Oncogenic Mutant <i>DNAJB</i>1<i>–PRKACA</i>
Journal of Proteome Research·2021· 8 citedOpen Access
Author Correction: Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A
Communications Biology·2021· 1 citedOpen Access
Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A
Communications Biology·2021· 28 citedOpen Access
Cyclic AMP dependent Protein Kinase A (PKA) mutant associated with Fibrolamellar Hepatocellular carcinoma (FLHCC): Structure, dynamics and in cell studies.
University of Minnesota Digital Conservancy (University of Minnesota)·2020Open Access
Cushing’s syndrome driver mutation disrupts protein kinase A allosteric network, altering both regulation and substrate specificity
Science Advances·2019· 66 citedOpen Access
A Cushing Syndrome Mutation of Protein Kinase A C‐subunit Disrupts the Internal Allosteric Network Affecting Regulation and Substrate Specificity
The FASEB Journal·2019· 1 cited
Abstract 4142: Conformational dynamics of the chimeric kinase DNAJB1-PRKACA, the driver for fibrolamellar hepatocellular carcinoma
Cancer Research·2018
Conformational Landscape of the PRKACA-DNAJB1 Chimeric Kinase, the Driver for Fibrolamellar Hepatocellular Carcinoma
Scientific Reports·2018· 29 citedOpen Access
Probing the Structural and Biochemical Basis for the Development of Cushing's Syndrome caused by a Somatic Mutant of Protein Kinase A
The FASEB Journal·2017
NMR Mapping of the Allosteric Network in the Oncogenic Protein Kinase A Chimera Dnajb1‐PRKACA
The FASEB Journal·2017
NMR Structural/Functional Characterization of an Oncogenic Mutant of cAMP-Dependent Protein Kinase A: PRKACA-DNAJB1
Biophysical Journal·2016Open Access

Frequent Co-authors

Susan S. Taylor(9), Gianluigi Veglia(9), Sanford M. Simon(6), Caitlin Walker(5), Cristina Olivieri(4), David Bernlohr(4), Yingjie Wang(3), David D. Thomas(3), Rui Pei(3), Jordan Casby(2), Kerstin Bathon(2), Davide Calebiro(2), Jiali Gao(2), Michael D. Tomasini(2), Yingjie Wang(2), Geoffrey Li(2), Thijs Beuming(2), V. S. Manu(2), Fernando Porcelli(2), Donald Blumenthal(2)