Wolfgang Löscher

Medizinische Hochschule Hannover — Germany

Medicine · Health Sciences

103h-index44.5kcitations727works13.22yr avg
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Research Topics

Epilepsy research and treatment(370), Neuroscience and Neuropharmacology Research(359), Pharmacological Effects and Toxicity Studies(261), Drug Transport and Resistance Mechanisms(138), Ion channel regulation and function(58)

Publications726 total

Breaking optical barriers: Transparent polymeric hollow fibers for biomedical applications
View·2025Open Access
Academia, industry and the slow adoption of new treatments
Brain·2025Open Access
Topiramate for the treatment of neonatal seizures and beyond
Epilepsia·2025Open Access
The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications. 1. Use of the <scp>EEG</scp> in drug development and characteristics of the model
Epilepsia·2025· 4 citedOpen Access
The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model
Epilepsia·2025· 5 citedOpen Access
Early postnatal inhibition of neurosteroid synthesis changes the later-life adverse outcome of neonatal asphyxia in rats
Neuropharmacology·2025Open Access
Pharmacodynamic interactions between seletracetam and antiseizure comedications in the human photosensitivity model
Epilepsia·2025Open Access
Clinical trials of prevention of acquired epilepsy: New proof‐of‐concept approach to restart trials
Epilepsia·2025· 2 cited
A multicenter Phase II randomized, placebo-controlled single-blind trial with the SV2A ligand seletracetam in photosensitive epilepsy patients
Epilepsy & Behavior·2025· 5 citedOpen Access
Animal welfare assessment after controlled cortical impact in CD-1 mice – A model of posttraumatic epilepsy
Epilepsy & Behavior·2024· 1 citedOpen Access
Novel antiseizure medications in the development pipeline: promising candidates and recent failures
Clinical Epileptology·2024· 5 citedOpen Access
Temporal development of seizure threshold and spontaneous seizures after neonatal asphyxia and the effect of prophylactic treatment with midazolam in rats
Experimental Neurology·2024· 2 citedOpen Access
A comparison of the antiepileptogenic efficacy of two rationally chosen multitargeted drug combinations in a rat model of posttraumatic epilepsy
Experimental Neurology·2024· 2 citedOpen Access
New epilepsy therapies in development
Nature Reviews Drug Discovery·2024· 101 cited
Drug Combinations for Antiepileptogenesis
2024· 2 cited
Mammalian models of status epilepticus – Their value and limitations
Epilepsy & Behavior·2024· 11 citedOpen Access
The impact of ATP-binding cassette transporters in the diseased brain: Context matters
Cell Reports Medicine·2024· 45 citedOpen Access
Heterogeneous brain distribution of bumetanide following systemic administration in rats
Biopharmaceutics & Drug Disposition·2024· 1 citedOpen Access
Tolerability of tariquidar – A third generation P-gp inhibitor as add-on medication to antiseizure medications in drug-resistant epilepsy
Seizure·2024· 4 citedOpen Access
Epilepsy and epileptiform activity in late-onset Alzheimer disease: clinical and pathophysiological advances, gaps and conundrums
Nature Reviews Neurology·2024· 73 cited
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Frequent Co-authors

Heidrun Potschka(14), Dieter Schmidt(8), Annamaria Vezzani(6), Michael A. Rogawski(5), Maren Fedrowitz(5), Claudia Brandt(4), Henrik Klitgaard(3), H. Steve White(3), Asla Pitkänen(3), Eleonora Aronica(3), Ulrich Ebert(3), Rafał M. Kamiński(3), Sanjay M. Sisodiya(2), Ingmar Blümcke(2), Michele Simonato(2), Alon Friedman(2), Jan A. Gorter(2), Teresa Ravizza(2), Pavel Klein(2), Dagmar Hönack(2)