Michael Chinkers

Lurie Children's Hospital — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

31h-index5.8kcitations45works0.02yr avg
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Research Topics

Heat shock proteins research(12), ATP Synthase and ATPases Research(8), Glycosylation and Glycoproteins Research(5), Viral Infectious Diseases and Gene Expression in Insects(5), Toxin Mechanisms and Immunotoxins(5)

Publications45 total

Abstract 4365172: Aortic Valve Type and Stenosis Can Be Identified from Wearable-Recorded Seismocardiograms Using Machine-Learned Classifiers
Circulation·2025
C-terminal sequences of hsp70 and hsp90 as non-specific anchors for tetratricopeptide repeat (TPR) proteins
Biochemical Journal·2009· 20 citedOpen Access
Protein Phosphatase 5 Is a Negative Modulator of Heat Shock Factor 1
Journal of Biological Chemistry·2005· 62 citedOpen Access
Functional Comparison of Human and Drosophila Hop Reveals Novel Role in Steroid Receptor Maturation
Journal of Biological Chemistry·2005· 51 citedOpen Access
Independent Functions of hsp90 in Neurotransmitter Release and in the Continuous Synaptic Cycling of AMPA Receptors
Journal of Neuroscience·2004· 87 citedOpen Access
PP5: the TPR phosphatase
Topics in current genetics·2003· 1 cited
Binding of hsp90-Associated Immunophilins to Cytoplasmic Dynein:  Direct Binding and in Vivo Evidence that the Peptidylprolyl Isomerase Domain Is a Dynein Interaction Domain
Biochemistry·2002· 116 cited
Identification of Potential Physiological Activators of Protein Phosphatase 5
Biochemistry·2002· 82 cited
Guanylate Cyclases
Wiley Encyclopedia of Molecular Medicine·2002
Identification of Amino Acids in the Tetratricopeptide Repeat and C-Terminal Domains of Protein Phosphatase 5 Involved in Autoinhibition and Lipid Activation
Biochemistry·2001· 96 cited
Regulation of the Atrial Natriuretic Peptide Receptor by Heat Shock Protein 90 Complexes
Journal of Biological Chemistry·2001· 43 citedOpen Access
Protein phosphatase 5 in signal transduction
Trends in Endocrinology and Metabolism·2001· 149 cited
Overlapping Sites of Tetratricopeptide Repeat Protein Binding and Chaperone Activity in Heat Shock Protein 90
Journal of Biological Chemistry·2000· 83 citedOpen Access
Cyclic Nucleotide-gated Channels Mediate Membrane Depolarization following Activation of Store-operated Calcium Entry in Endothelial Cells
Journal of Biological Chemistry·2000· 62 citedOpen Access
Identification of Conserved Residues Required for the Binding of a Tetratricopeptide Repeat Domain to Heat Shock Protein 90
Journal of Biological Chemistry·1999· 165 citedOpen Access
High-Molecular-Weight FK506-Binding Proteins Are Components of Heat-Shock Protein 90 Heterocomplexes in Wheat Germ Lysate
PLANT PHYSIOLOGY·1998· 62 cited
p50 Binds Directly to the Catalytic Domain of Raf as Well as to a Site on hsp90 That Is Topologically Adjacent to the Tetratricopeptide Repeat Binding Site
Journal of Biological Chemistry·1998· 117 citedOpen Access
Mapping of Ppp5c, the gene encoding protein phosphatase 5, to mouse Chromosome 7
Mammalian Genome·1997· 1 cited
Protein Phosphatase 5 Is a Major Component of Glucocorticoid Receptor·hsp90 Complexes with Properties of an FK506-binding Immunophilin
Journal of Biological Chemistry·1997· 256 citedOpen Access
The Tetratricopeptide Repeat Domain of Protein Phosphatase 5 Mediates Binding to Glucocorticoid Receptor Heterocomplexes and Acts as a Dominant Negative Mutant
Journal of Biological Chemistry·1996· 223 citedOpen Access
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Frequent Co-authors

David L. Garbers(11), William B. Pratt(5), Stanley Cohen(4), Adam M. Silverstein(4), Lance C. Russell(4), David Lowe(3), David V. Goeddel(3), Sujay Singh(3), Sherry R. Whitt(3), Andrew J. Ramsey(3), Joan S. Brugge(3), Stephanie Schulz(2), J A McKanna(2), David Thorpe(2), Lawrence J. Dangott(2), Mario D. Galigniana(2), Mei-Shya Chen(2), Elizabeth M. Wilson(2), Nicholas Grammatikakis(2), Jennifer M. Harrell(2)