Ashlesha Deshpande

University of Alabama at Birmingham — United States

Medicine · Health Sciences

17h-index1.1kcitations43works1.72yr avg
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Research Topics

Cytomegalovirus and herpesvirus research(8), SARS-CoV-2 and COVID-19 Research(7), Analytical Chemistry and Chromatography(6), HIV Research and Treatment(5), Enzyme Catalysis and Immobilization(5)

Publications43 total

Characterization of full-length and cytoplasmic tail-truncated envelope glycoproteins incorporated into human immunodeficiency virus (HIV-1) virions and virus-like particles
Journal of Virology·2025· 1 citedOpen Access
Characterization of full-length and cytoplasmic tail-truncated envelope glycoproteins incorporated into human immunodeficiency virus (HIV-1) virions and virus-like particles
2025· 2 citedOpen Access
Inducible cell lines producing replication-defective human immunodeficiency virus particles containing envelope glycoproteins stabilized in a pretriggered conformation
Journal of Virology·2024· 2 citedOpen Access
Structure and epitope of a neutralizing monoclonal antibody that targets the stem helix of β coronaviruses
FEBS Journal·2023· 6 citedOpen Access
Structure and Epitope of a Neutralizing Monoclonal Antibody that Targets the Stem Helix of β Coronaviruses
2022· 1 citedOpen Access
Potent universal beta-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody
PLoS Pathogens·2022· 37 citedOpen Access
Functional and Highly Cross-Linkable HIV-1 Envelope Glycoproteins Enriched in a Pretriggered Conformation
Journal of Virology·2022· 23 citedOpen Access
Functional and Highly Crosslinkable HIV-1 Envelope Glycoproteins Enriched in a Pretriggered Conformation
2021· 2 citedOpen Access
Epitope Classification and RBD Binding Properties of Neutralizing Antibodies Against SARS-CoV-2 Variants of Concern
Frontiers in Immunology·2021· 103 citedOpen Access
Epitope classification and RBD binding properties of neutralizing antibodies against SARS-CoV-2 variants of concern
2021· 3 citedOpen Access
Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters
Cell Reports Medicine·2021· 72 citedOpen Access
Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters
2020· 22 citedOpen Access
Characterization of Type-I IFN subtype autoantibodies and activity in SLE serum and urine
Lupus·2020· 15 citedOpen Access
Neutralization of rhesus cytomegalovirus IL-10 reduces horizontal transmission and alters long-term immunity
Proceedings of the National Academy of Sciences·2019· 15 citedOpen Access
Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys
JCI Insight·2017· 77 citedOpen Access
Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys
2017· 3 citedOpen Access
Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission
Clinical and Vaccine Immunology·2017· 18 citedOpen Access
Exploitation of Interleukin-10 (IL-10) Signaling Pathways: Alternate Roles of Viral and Cellular IL-10 in Rhesus Cytomegalovirus Infection
Journal of Virology·2016· 18 citedOpen Access
Cytokine Activation by Antibody Fragments Targeted to Cytokine-Receptor Signaling Complexes
Journal of Biological Chemistry·2015· 10 citedOpen Access
Vaccination against a Virus-Encoded Cytokine Significantly Restricts Viral Challenge
Journal of Virology·2013· 30 citedOpen Access
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Frequent Co-authors

Mark R. Walter(20), Nitin W. Fadnavis(11), Luis Martínez‐Sobrido(7), James J. Kobie(7), Bethany D. Harris(6), Peter A. Barry(6), Hanh T. Nguyen(5), Saumya Anang(5), Shijian Zhang(5), Haitao Ding(5), John C. Kappes(5), Joseph Sodroski(5), Ravi Luke Babu(5), Paul A. Goepfert(4), Gurrala Sheelu(4), Srilalitha Kuruganti(4), Cody S. Nelson(3), Kristy M. Bialas(3), Flavia Chiuppesi(3), Felix Wussow(3)