Jay M. McDonald

University of Alabama at Birmingham — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

53h-index11.1kcitations229works0.02yr avg
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Research Topics

Metabolism, Diabetes, and Cancer(33), Protein Kinase Regulation and GTPase Signaling(27), Cell death mechanisms and regulation(27), Bone Metabolism and Diseases(26), Pancreatic function and diabetes(22)

Publications229 total

Regulation of pancreatic cancer TRAIL resistance by protein O-GlcNAcylation
Laboratory Investigation·2020· 33 citedOpen Access
Cytoplasmic PARP‐1 promotes pancreatic cancer tumorigenesis and resistance
International Journal of Cancer·2019· 30 citedOpen Access
The long non-coding RNA HOTAIR enhances pancreatic cancer resistance to TNF-related apoptosis-inducing ligand
Journal of Biological Chemistry·2017· 83 citedOpen Access
Calmodulin antagonists promote TRA-8 therapy of resistant pancreatic cancer
Oncotarget·2015· 31 citedOpen Access
Characteristics of Great Leaders
SMARTech Repository (Georgia Institute of Technology)·2015
Pancreatic Cancer Resistance to TRAIL Therapy: Regulators of the Death Inducing Signaling Complex
Resistance to targeted anti-cancer therapeutics·2015
Author Argues Have-nots Better Served by Postal Banking
2015Open Access
Abstract 2268: Augmentation of DR5 expression by calmodulin antagonists sensitizes TRA-8-induced apoptosis in pancreatic cancer
Cancer Research·2014
Characterization of Calmodulin–Fas Death Domain Interaction: An Integrated Experimental and Computational Study
Biochemistry·2014· 12 citedOpen Access
Safety and effectiveness of a glistening-free single-piece hydrophobic acrylic intraocular lens (enVista)
Clinical ophthalmology·2013· 39 citedOpen Access
PARP-1 Regulates Resistance of Pancreatic Cancer to TRAIL Therapy
Clinical Cancer Research·2013· 64 citedOpen Access
Abstract 2947: PARP-1 regulates death receptor 5-mediated apoptosis in pancreatic cancer.
Cancer Research·2013
Abstract 2953: Inhibition of calmodulin enhances TRA-8-induced apoptosis in pancreatic cancer cells .
Cancer Research·2013
Structural insight for the roles of fas death domain binding to fadd and oligomerization degree of the fas–fadd complex in the death‐inducing signaling complex formation: A computational study
Proteins Structure Function and Bioinformatics·2012· 11 cited
Table of Contents
American Journal Of Pathology·2012Open Access
The Dark Side of Publishing
American Journal Of Pathology·2012· 47 citedOpen Access
Abstract 4754: Quantitative characterization of calmodulin and Fas death domain interactions
Cancer Research·2012
Abstract 246: Calmodulin binding to death receptor-5 regulates pancreatic cancer apoptosis
Cancer Research·2012
Reduced CaM/FLIP binding by a single point mutation in c-FLIPL modulates Fas-mediated apoptosis and decreases tumorigenesis
Laboratory Investigation·2011· 9 citedOpen Access
Calmodulin Mediates Fas-induced FADD-independent Survival Signaling in Pancreatic Cancer Cells via Activation of Src-Extracellular Signal-regulated Kinase (ERK)
Journal of Biological Chemistry·2011· 50 citedOpen Access
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Frequent Co-authors

Majd Zayzafoon(8), George Pan(8), David B. Sacks(7), Leonard Jarett(7), David E. Bruns(6), Harrihar A. Pershadsingh(4), Margaret A. McKenna(4), Xu Feng(3), Yabing Chen(3), Valerie Meyers(3), Robert W. Hardy(3), Jack H. Ladenson(3), Xiaojun Wu(3), David E. Goldstein(2), Noel K. Maclaren(2), Marian Parrott(2), William E. Gathings(2), James E. Davis(2), Jodie Williford(2), Wen‐Cheng Xiong(2)