Stefan Günther

University of Freiburg — Germany

Computer Science · Physical Sciences

37h-index6.1kcitations181works3.12yr avg
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Research Topics

Computational Drug Discovery Methods(36), Microbial Natural Products and Biosynthesis(25), Protein Degradation and Inhibitors(15), Protein Structure and Dynamics(11), Histone Deacetylase Inhibitors Research(9)

Publications180 total

Soluble epoxide hydrolase in Alzheimer’s disease drives neurovascular dysfunction
2025Open Access
The NMDA receptor subunit GluN2D is a potential target for rapid antidepressant action
Nature Communications·2025· 2 citedOpen Access
African Natural Products Database (ANPDB): A resource for exploring the therapeutic potential of natural compounds from Africa
Nucleic Acids Research·2025Open Access
Unraveling the role of CACNA1F, RASAL1, GARIN4, and TRIM56 in common opioid side effects via transcriptomic analysis of differentiated neuron-like SH-SY5Y cells
2025Open Access
Differentiation hierarchy in adult B cell acute lymphoblastic leukemia at clonal resolution
2025Open Access
Deletion of ABIN1-LIR motifs impairs hepatic lipid homeostasis and mitophagy via AMPK-TFEB axis in mice
American Journal of Physiology-Cell Physiology·2025Open Access
LRBA deficiency impairs autophagy and contributes to enhanced antigen presentation and T-cell dysregulation
EMBO Reports·2025Open Access
Structure-Guided Design of a KMT9 Inhibitor Prodrug with Cellular Activity
Journal of Medicinal Chemistry·2025Open Access
On the Quest for Biomarkers: A Comprehensive Analysis of Modified Nucleosides in Ovarian Cancer Cell Lines
Cells·2025Open Access
Correction: Pfäffle et al. A 14-Day Double-Blind, Randomized, Controlled Crossover Intervention Study with Anti-Bacterial Benzyl Isothiocyanate from Nasturtium (Tropaeolum majus) on Human Gut Microbiome and Host Defense. Nutrients 2024, 16, 373
Nutrients·2025Open Access
Binding Free Energy Calculations for Bromodomain Ligands: A Binding Affinity Tool-Based Approach
2025Open Access
A Novel Inhibitor against the Bromodomain Protein 1 of the Malaria Pathogen <i>Plasmodium Falciparum</i>
ChemMedChem·2025· 3 citedOpen Access
Synthesis and Biological Evaluation of Metamorphine: A Morphine–Metamizole Adduct from Patient-Controlled Analgesia Pumps
ACS Pharmacology & Translational Science·2025· 1 citedOpen Access
A novel inhibitor against the bromodomain <i>Pf</i> BDP1 of the malaria pathogen <i>Plasmodium falciparum</i>
2025Open Access
StreptomeDB 4.0: a comprehensive database of streptomycetes natural products enriched with protein interactions and interactive spectral visualization
Nucleic Acids Research·2024· 9 citedOpen Access
Front Cover: Development of a NanoBRET Assay Platform to Detect Intracellular Ligands for the Chemokine Receptors CCR6 and CXCR1 (ChemMedChem 20/2024)
ChemMedChem·2024Open Access
The NMDA receptor subunit GluN2D is a target for rapid antidepressant action
2024· 1 citedOpen Access
SPMs exert anti-inflammatory and pro-resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor
Proceedings of the National Academy of Sciences·2024· 37 citedOpen Access
A regulatory loop involving the cytochrome P450-soluble epoxide hydrolase axis and TGF-β signaling
iScience·2024· 1 citedOpen Access
Development of a NanoBRET Assay Platform to Detect Intracellular Ligands for the Chemokine Receptors CCR6 and CXCR1
ChemMedChem·2024· 6 citedOpen Access
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Frequent Co-authors

Aurélien F. A. Moumbock(9), Björn Grüning(8), Robert Preißner(7), Pankaj Mishra(7), Xavier Lucas(6), Fidele Ntie‐Kang(5), Martin Hügle(5), Kiran K. Telukunta(4), Conrad V. Simoben(4), Wolfgang Sippl(4), Daniel Wohlwend(4), Wolfgang Hüttel(4), Michael Müller(4), Irmgard Merfort(4), Christian Senger(3), Kersten Döring(3), Anika Erxleben(3), Susana Minguet(3), Matthias Schmidt(3), S. Gerhardt(3)