Declan Whyte

University Medical Center Groningen — Netherlands

Medicine · Health Sciences

6h-index224citations58works0.92yr avg
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Research Topics

Cell Adhesion Molecules Research(44), Immune cells in cancer(44), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(29), Chemokine receptors and signaling(15), Pancreatic and Hepatic Oncology Research(8)

Publications58 total

Uridine phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes
EMBO Reports·2025· 3 citedOpen Access
Correction: Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-Specific Neutrophils
Cancer Research Communications·2025Open Access
A compendium of Amplification-Related Gain Of Sensitivity genes in human cancer
Nature Communications·2025· 11 citedOpen Access
Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung
2024Open Access
NUAK: never underestimate a kinase
Essays in Biochemistry·2024· 12 citedOpen Access
IL-27 maintains cytotoxic Ly6C+ γδ T cells that arise from immature precursors
The EMBO Journal·2024· 6 citedOpen Access
Abstract 6806: Single cell RNA sequencing of human and murine cancers demonstrates metastases-specific neutrophil phenotypes driven by the IL-1β/CXCR2 signaling axis - Disruption of this pathway abrogates neutrophil immunosuppressive effects and reduces tumor burden
Cancer Research·2024
Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer
2024· 3 citedOpen Access
Data from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
Supplementary Figure S7 from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
Supplementary Figure S8 from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
FIGURE 5 from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
Supplementary Figure S5 from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
TABLE 1 from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
Supplementary Tables from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
FIGURE 1 from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
Supplementary Figure S6 from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
Supplementary Figure S9 from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
Supplementary Figure S6 from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
TABLE 2 from Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils
2024Open Access
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Frequent Co-authors

Colin Nixon(47), Leo M. Carlin(45), Owen J. Sansom(44), Jim C. Norman(39), Cassie J. Clarke(38), René Jackstadt(38), Kathryn Gilroy(37), Colin W. Steele(37), Rana Fetit(36), Alistair S. McLaren(36), Mark White(36), Megan L. Mills(36), John Falconer(36), Xabier Cortés-Lavaud(36), Tamsin R.M. Lannagan(36), Rachel A. Ridgway(36), Varushka Naiker(36), Renee Njunge(36), Kristina Kirschner(36), Andrew D. Campbell(36)