Marwa Sharaky

Cairo University — Egypt

Chemistry · Physical Sciences

17h-index1.4kcitations106works4.72yr avg
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Research Topics

Synthesis and biological activity(39), Click Chemistry and Applications(15), Cancer therapeutics and mechanisms(15), Synthesis and Characterization of Heterocyclic Compounds(14), Estrogen and related hormone effects(7)

Publications106 total

Fragment merging design, synthesis, and biological evaluation of novel methyl Selanyl– And thiazolidinedione-based hybrids as potent anticancer inducing apoptosis and cell cycle arrest
Bioorganic & Medicinal Chemistry·2026
Investigating the Telomerase Downregulatory Potential of Steroidal Drugs Following Pharmacophore‐Based Rational; Computational and In Vitro Assessments
Archiv der Pharmazie·2026
Author response for "Targeting Cell Cycle and Apoptotic Pathways with Newly Synthesized Diselenide-linked Imidazolone Analogues with Great Potential Towards CDK"
2026
Author response for "Organoselenium-Based Schiff Bases and Amidic Acid Derivatives as Promising Anticancer Agents Targeting Breast Cancer by Downregulating BCL-2: Design, Synthesis, and Biological Evaluation"
2026
Targeting cell cycle and apoptotic pathways with newly synthesized diselenide-linked imidazolone analogues with strong CDK6-targeting potential
RSC Advances·2026· 1 citedOpen Access
Organoselenium-based Schiff bases and amidic acid derivatives as promising anticancer agents targeting breast cancer by downregulating BCL-2: design, synthesis, and biological evaluation
RSC Advances·2026· 1 citedOpen Access
Exploring the apoptosis-inducing potential of Syzygium cimini leaves in cancer treatment; LC-ESI-MS/MS analysis, biological assessments, and computational studies
Scientific African·2025Open Access
Leveraging the Fragment Merging Approach for Synthetizing Novel Selanyl Phenyl Acetamide Thiazolidinedione Hybrids Endowed With Apoptotic Potential for Cancer Treatment
Drug Development Research·2025· 3 cited
Multi‐Target Rational Design and Synthesis of Some 2‐Quinolinone Antitumor Candidates Downregulating the Expression of EGFR, VEGFR‐2, and Telomerase With Apoptotic Potential
Drug Development Research·2025
Harnessing Fragment Merging and Chain Extension Approaches for Designing Phthalimidoalkyl‐Arylidene Thiazolidinedione Hybrids: New Frontiers in Apoptosis‐Inducing Cancer Treatment
Archiv der Pharmazie·2025· 4 cited
Carnitine deficiency augments methotrexate-mediated acute renal injury in rats
Journal of the Egyptian National Cancer Institute·2025Open Access
Author response for "Isatin, a monoamine oxidase inhibitor, sensitizes resistant breast cancer cells to tamoxifen <i>via</i> MAO-A/HIF1α/MMPs modulation"
2025
Design and Synthesis of New Multi‐Target Coumarin Analogues Acting as Carbonic Anhydrases IX/XII and Topoisomerase II Inhibitors With Apoptotic Potential
Archiv der Pharmazie·2025
Rutin Alleviates Breast Cancer Resistance to Tamoxifen By Downregulating ABC Transporters, Inducing ROS Generation and Resetting Redox Status
Journal of Biochemical and Molecular Toxicology·2025· 1 citedOpen Access
Discovery of Furopyrimidine‐Pyrazole Hybrid Compounds Targeting p53‐MDM2 Interaction as Anticancer Agents
Archiv der Pharmazie·2025
Exploring the Topoisomerase II Inhibitory Potential of Steroidal Drugs as a Recommended Mechanism of Action for Their Anticancer Activity: <i>In Silico</i> and <i>In Vitro</i> Assessments
Drug Development Research·2025
Corrigendum to “Xanthone-loaded niosomes as innovative potential delivery platform: Formulation, characterization, and cytotoxic effect on human cancer cell lines” [J. Drug Deliv. Sci. Technol. (2024) 102, Part B (2024) 106384]
Journal of Drug Delivery Science and Technology·2025
Folate-based binuclear Mn(II) chelates with 2,2’-bipyridine/1,10-phenanthroline as targeted anticancer agents for colon cancer cells
Scientific Reports·2025· 1 citedOpen Access
Novel Diselenide Bis-Schiff bases tagged with diphenyl ethers: Promising candidates for selective treatment of hypopharyngeal and breast adenocarcinoma
Bioorganic Chemistry·2025· 6 cited
Synthesis, cytotoxicity, oxidative stress, anti-metastatic and anti-inflammatory effects of novel 2-methylene-1H-indene-1,3-dione tethered 2-(2-methoxyphenoxy)-N-arylacetamide: induction of apoptosis in HCT116 and HeLa cells
Chemico-Biological Interactions·2025· 9 cited
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Frequent Co-authors

Ahmed A. Al‐Karmalawy(22), Ayman Abo Elmaaty(8), Amna H. Faid(7), Saad Shaaban(6), Wagdy M. Eldehna(5), Ahmed H. M. Elwahy(5), Samia A. Shouman(4), Mervat M. Omran(4), Ahmed M. El‐Dessouki(4), Radwan Alnajjar(4), Haytham O. Tawfik(4), Ismail A. Abdelhamid(4), Marwa A. Ramadan(4), Marwa Abdel‐Motaal(3), Yehia Badr(3), Khaled A. M. Abouzid(3), Mai H. A. Mousa(3), Mai A.E. Mourad(3), Moataz A. Shaldam(3), Mohamed M. Hammouda(3)