Nathalie Franchimont

Biogen (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index3.7kcitations125works6.42yr avg
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Research Topics

Bone Metabolism and Diseases(35), Systemic Lupus Erythematosus Research(26), Monoclonal and Polyclonal Antibodies Research(22), Bone health and treatments(21), Bone health and osteoporosis research(18)

Publications125 total

Safety and efficacy of opicinumab in participants with relapsing multiple sclerosis (AFFINITY Part 1): A randomized, controlled, phase 2 trial
Multiple Sclerosis Journal·2025
Pharmacodynamic Effects of Litifilimab in Lupus in a Randomized, Placebo‐Controlled Phase 2 Study: Rapid and Sustained Reductions in Type I Interferon‐Associated Gene Expression and Cytokines
Arthritis & Rheumatology·2025· 3 citedOpen Access
Part B of the LILAC study of litifilimab for cutaneous lupus erythematosus: a plain language summary
Immunotherapy·2025· 1 citedOpen Access
Part A of the LILAC study of litifilimab for systemic lupus erythematosus: a plain language summary
Immunotherapy·2025· 2 citedOpen Access
RENEWED: A follow-up study of the opicinumab phase 2 RENEW study in participants with acute optic neuritis
Multiple Sclerosis and Related Disorders·2024· 7 citedOpen Access
Tyrosine Kinase 2 Inhibition With Zasocitinib (TAK-279) in Psoriasis
JAMA Dermatology·2024· 30 citedOpen Access
Editorial: Cutaneous lupus erythematosus landscape: pathophysiology, unmet needs, and related challenges in clinical practice. What is on the horizon?
Frontiers in Medicine·2024· 2 citedOpen Access
Anti-BDCA2 Antibody for Cutaneous Lupus Erythematosus
New England Journal of Medicine·2022· 3 cited
Effect of Dimethyl Fumarate vs Interferon β-1a in Patients With Pediatric-Onset Multiple Sclerosis
JAMA Network Open·2022· 50 citedOpen Access
PO.4.75 The anti-BDCA2 antibody biib059 improves joint and skin manifestations in patients with SLE and both active arthritis and rash
2022Open Access
Trial of Anti-BDCA2 Antibody Litifilimab for Systemic Lupus Erythematosus
New England Journal of Medicine·2022· 110 citedOpen Access
Trial of Anti-BDCA2 Antibody Litifilimab for Cutaneous Lupus Erythematosus
New England Journal of Medicine·2022· 120 citedOpen Access
Chronic lesion activity and disability progression in secondary progressive multiple sclerosis
BMJ Neurology Open·2022· 39 citedOpen Access
Machine Learning-Based Detection of Slowly Expanding Lesions using Radiomic Features from Cross-sectional Brain MRI (S26.004)
Neurology·2022
Machine Learning-Based Prediction of New Multiple Sclerosis Lesion Formation Using Radiomic Features from Pre-Lesion Normal Appearing White Matter (S26.009)
Neurology·2022· 1 cited
CONNECT : étude ouverte, avec contrôle actif, portant sur le diméthylfumarate (DMF) chez des patients pédiatriques atteints de sclérose en plaques récurrente-rémittente
Revue Neurologique·2022
27475 Efficacy of the BIIB059 monoclonal antibody against BDCA2 in active cutaneous lupus erythematosus (CLE): Subgroup analyses of participants with or without systemic LE (SLE) and with different levels of disease activity
Journal of the American Academy of Dermatology·2021
MOG autoantibodies trigger a tightly-controlled FcR and BTK-driven microglia proliferative response
Brain·2021· 59 citedOpen Access
POS0698 BIIB059 DEMONSTRATED A CONSISTENT THERAPEUTIC EFFECT ON SRI-4 RESPONSE ACROSS SUBGROUPS OF PARTICIPANTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS IN THE LILAC PHASE 2 STUDY
Annals of the Rheumatic Diseases·2021· 1 citedOpen Access
POS0699 GREATER REDUCTION IN CLASI-A SCORES ACHIEVED WITH BIIB059 VERSUS PLACEBO INDEPENDENTLY OF DISEASE SEVERITY AT BASELINE
Annals of the Rheumatic Diseases·2021
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Frequent Co-authors

Michel Malaise(14), Ernesto Canalis(8), Vincent Bours(7), Marie‐Paule Merville(7), Marie-Joëlle Kaiser(6), Victoria P. Werth(5), Richard Furie(4), Alex Pellerin(4), Catherine Barbey(4), Clio Ribbens(4), Jeremy C. Burns(4), Michaël Mingueneau(4), Sheila Rydziel(4), Matthew Scaramozza(4), Biserka Relić(4), Shibeshih Belachew(4), Vincent Geenen(3), Juanita Romero‐Díaz(3), Sandra Navarra(3), Kenneth Kalunian(3)