Dejian Ren

University of Pennsylvania — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

41h-index9.2kcitations77works3.62yr avg
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Research Topics

Ion channel regulation and function(30), Calcium signaling and nucleotide metabolism(24), Sperm and Testicular Function(12), Ion Channels and Receptors(12), Cellular transport and secretion(11)

Publications77 total

TMEM175 does not function as a proton-selective ion channel to prevent lysosomal over-acidification
The Journal of Cell Biology·2025· 4 cited
Artificial intelligence coaches on the sidelines: Evaluating readability and quality of soccer training plans from six generative models
International Journal of Sports Science & Coaching·2025· 1 cited
Use the rating of perceived exertion to evaluate load in collegiate male soccer player, validity and influencing factors
Scientific Reports·2025· 2 citedOpen Access
Lysosomal channels sensing forces
Nature Cell Biology·2024· 2 cited
Two-pore channels regulate endomembrane tension to enable remodeling and resolution of phagolysosomes
Proceedings of the National Academy of Sciences·2024· 9 citedOpen Access
The Concise Guide to PHARMACOLOGY 2023/24: Ion channels
British Journal of Pharmacology·2023· 181 citedOpen Access
A new neurodevelopmental disorder linked to heterozygous variants in UNC79
Genetics in Medicine·2023· 22 citedOpen Access
The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
eLife·2023· 64 citedOpen Access
Author response: The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
2023Open Access
Lysosomal Ion Channels: What Are They Good For and Are They Druggable Targets?
The Annual Review of Pharmacology and Toxicology·2022· 44 citedOpen Access
The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins
2022· 4 citedOpen Access
CatSper and Two-Pore channels (TPC) in GtoPdb v.2022.1
IUPHAR/BPS Guide to Pharmacology CITE·2022Open Access
CLN7 is an organellar chloride channel regulating lysosomal function
Science Advances·2021· 46 citedOpen Access
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels
British Journal of Pharmacology·2021· 248 citedOpen Access
Author Correction: A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology
Nature·2021· 6 citedOpen Access
A growth-factor-activated lysosomal K+ channel regulates Parkinson’s pathology
Nature·2021· 111 citedOpen Access
Epilepsy-associated Mutations in the Calcium-sensing Receptor Disrupt the Regulation of NALCN Sodium-leak Channel by Extracellular Calcium in Neurons
2020· 1 citedOpen Access
Flow Field Simulation Analysis of Train Siphon Toilet with Variable Pipe Diameter Based on the Investigation of Siphon Performance
Journal of Physics Conference Series·2020Open Access
Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex
Nature Communications·2020· 26 citedOpen Access
Decision letter: Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function
2020Open Access
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Frequent Co-authors

David E. Clapham(11), Chunlei Cang(11), Jingsheng Xia(7), Kimberly Aranda(7), Haoxing Xu(6), Betsy Navarro(6), Linda M. Hall(5), Lixia Yue(4), Boxun Lu(4), Haikun Wang(4), Daniel F. Eberl(4), Xiaoli Zhang(3), Yandong Zhou(3), Michael X. Zhu(3), Martin Biel(3), Stefanie Fenske(3), Jinhong Wie(3), Qing Shi(2), Yanhua Su(2), Sudipto Das(2)