David J. Owen

University of Cambridge — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

53h-index12.0kcitations119works1.92yr avg
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Research Topics

Cellular transport and secretion(79), Lipid Membrane Structure and Behavior(38), Endoplasmic Reticulum Stress and Disease(14), Erythrocyte Function and Pathophysiology(11), Glycosylation and Glycoproteins Research(8)

Publications119 total

Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks
Nature Communications·2025Open Access
The mechanistic basis of cargo selection during Golgi maturation
Science Advances·2025Open Access
RABGAP1 is a sensor that facilitates the sorting and processing of amyloid precursor protein
The EMBO Journal·2025Open Access
Combined thermodynamic and time-resolved structural analysis of interactions between AP2 and biomimetic plasma membranes provides insights into clathrin-mediated endocytosis
Communications Biology·2025Open Access
Structural molecular details of the endocytic adaptor protein CALM upon binding with phosphatidylinositol 4,5-bisphosphate-containing model membranes
Communications Chemistry·2025· 2 citedOpen Access
The mechanistic basis of cargo selection during Golgi maturation
2025Open Access
α-Synuclein interacts directly with AP2 and regulates its binding to synaptic membranes
Journal of Biological Chemistry·2025· 5 citedOpen Access
Engineering Curvature: Block Copolymer Lithography for the Fabrication of Curved Lipid Membranes and Their Impact on Protein-Membrane Interactions
2025Open Access
Engineering curvature: block copolymer lithography for the fabrication of curved lipid membranes and their impact on protein–membrane interactions
Journal of Materials Chemistry B·2025Open Access
Untangling structural molecular details of the endocytic adaptor protein CALM upon binding with phosphatidylinositol 4,5-bisphosphate-containing model membranes
2024Open Access
RABGAP1 acts as a sensor to facilitate sorting and processing of amyloid precursor protein
2024· 1 citedOpen Access
Cargo selective vesicle tethering: The structural basis for binding of specific cargo proteins by the Golgi tether component TBC1D23
Science Advances·2024· 13 citedOpen Access
Repurposing an endogenous degradation domain for antibody-mediated disposal of cell-surface proteins
EMBO Reports·2024· 4 citedOpen Access
Cargo selective vesicle tethering: the structural basis for binding of specific cargo proteins by the Golgi tether component TBC1D23
2023Open Access
Engineering phosphatidylinositol-4,5-bisphosphate model membranes enriched in endocytic cargo: A neutron reflectometry, AFM and QCM-D structural study
Colloids and Surfaces B Biointerfaces·2023· 6 citedOpen Access
Engineering Phosphatidylinositol-4,5-bisphosphate model membranes enriched 1 in endocytic cargo: a neutron reflectometry, AFM and QCM-D structural study
2023Open Access
Engineering Phosphatidylinositol-4,5-Bisphosphate Model Membranes Enriched in Endocytic Cargo: A Neutron Reflectometry, AFM and QCM-D Structural Study
SSRN Electronic Journal·2023Open Access
Obstetrics
2022
Answers: Obstetrics
2022
HPV-16 E7 Interacts with the Endocytic Machinery via the AP2 Adaptor μ2 Subunit
mBio·2022· 13 citedOpen Access
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Frequent Co-authors

Philip R. Evans(16), Brett M. Collins(12), J. Paul Luzio(7), Stefan Höning(6), Stuart R. Gray(6), Harvey T. McMahon(5), Airlie J. McCoy(5), B.T. Kelly(5), Margaret S. Robinson(5), Melissa A. Edeling(5), Yvonne Vallis(4), Helen M. Kent(4), Lauren P. Jackson(4), Stephen C. Graham(4), Peter J. Watson(4), M.E.M. Noble(3), Sharon Miller(3), Alison M. Motley(3), Oleksiy Kovtun(3), Rohan D. Teasdale(3)