Sophie D. Lefevre

Inserm — France

Medicine · Health Sciences

23h-index1.6kcitations47works2.32yr avg
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Research Topics

Erythrocyte Function and Pathophysiology(17), Mitochondrial Function and Pathology(9), Hemoglobinopathies and Related Disorders(9), Genetic Neurodegenerative Diseases(6), Heme Oxygenase-1 and Carbon Monoxide(5)

Publications47 total

Pharmacological inhibition of polrmt mimicking polrmt rare variants associated with sideroblastic anemia, strongly inhibits proliferation and differentiation of human erythroblasts
Blood·2025Open Access
Abstract 1492: Clinical validation on the PAOLA-1/ENGOT-ov25 cohort of HRD calculation performed with the OncoDEEP® kit comprehensive genomic panel
Cancer Research·2025
Mitochondrial retention in mature red blood cells from patients with sickle cell disease is associated with stress erythropoiesis but not with proinflammatory state
HemaSphere·2024· 1 citedOpen Access
Coinfection accelerates transmission to new hosts despite no effects on virulence and parasite growth
Philosophical Transactions of the Royal Society B Biological Sciences·2024· 8 citedOpen Access
Intraspecific density changes the impact of interspecific competitors on parasite infection traits in multiple infections
2023Open Access
Oxidative Stress in Healthy and Pathological Red Blood Cells
Biomolecules·2023· 115 citedOpen Access
Limited host availability disrupts the genetic correlation between virulence and transmission
Evolution Letters·2023· 10 citedOpen Access
<i>HEATR3</i> variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia
Blood·2022· 36 citedOpen Access
Transmission Electron Microscopy to Follow Ultrastructural Modifications of Erythroblasts Upon ex vivo Human Erythropoiesis
Frontiers in Physiology·2022· 14 citedOpen Access
« L’Épée (du siècle) »
Spotlight·2022Open Access
Deficient mitophagy pathways in sickle cell disease
British Journal of Haematology·2021· 31 citedOpen Access
Human erythroid differentiation requires VDAC1-mediated mitochondrial clearance
Haematologica·2021· 26 citedOpen Access
Downregulation of Mitochondrial TSPO Inhibits Mitophagy and Reduces Enucleation During Human Terminal Erythropoiesis
International Journal of Molecular Sciences·2020· 23 citedOpen Access
Oxidative stress activates red cell adhesion to laminin in sickle cell disease
Haematologica·2020· 25 citedOpen Access
An Overview of Different Strategies to Recreate the Physiological Environment in Experimental Erythropoiesis
International Journal of Molecular Sciences·2020· 11 citedOpen Access
TSPO2 translocates 5‐aminolevulinic acid into human erythroleukemia cells
Biology of the Cell·2020· 9 citedOpen Access
A New Prevalent Densovirus Discovered in Acari. Insight from Metagenomics in Viral Communities Associated with Two-Spotted Mite (Tetranychus urticae) Populations
Viruses·2019· 31 citedOpen Access
Abstract P5-12-05: Phenotypic discordance between primary and metastatic breast cancer (MBC) in a large scale real-life multicentre French cohort
Cancer Research·2019
Regulation of extracellular ATP of human erythrocytes treated with α-hemolysin. Effects of cell volume, morphology, rheology and hemolysis
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2019· 14 citedOpen Access
Induction of ATP Release, PPIX Transport, and Cholesterol Uptake by Human Red Blood Cells Using a New Family of TSPO Ligands
International Journal of Molecular Sciences·2018· 8 citedOpen Access
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Frequent Co-authors

Mariano A. Ostuni(15), Caroline Le Van Kim(12), Martina Moras(8), Claude Hattab(8), Renata Santos(6), Wassim El Nemer(6), Bruno Le Pioufle(6), Olivier Français(6), Jean‐Michel Camadro(5), Ida J. van der Klei(4), Irene Marginedas-Freixa(4), Pablo J. Schwarzbaum(4), Alison B. Duncan(4), Leonor R. Rodrigues(4), Dominika Sliwa(3), Emmanuel Lesuisse(3), Valentine Brousse(3), Michaël Dussiot(3), Claudine Lapouméroulie(3), Marten Veenhuis(3)