Michael C. Jensen

Seattle Children's Hospital — United States

Medicine · Health Sciences

80h-index33.1kcitations628works6.12yr avg
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Research Topics

CAR-T cell therapy research(413), Immune Cell Function and Interaction(101), Immunotherapy and Immune Responses(98), Virus-based gene therapy research(68), Nanowire Synthesis and Applications(34)

Publications627 total

Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma
Neuro-Oncology·2026· 1 cited
Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma
Nature Communications·2025· 2 citedOpen Access
CTIM-38. PIONEERING QUAD-TARGETING CAR T CELL THERAPY IN PEDIATRIC CNS TUMORS – ANALYSIS FROM THE FIRST-IN-HUMAN PHASE 1 TRIAL BRAINCHILD-04
Neuro-Oncology·2025Open Access
263 Engineering mercaptopurine-resistant CD19CAR T cells with a mutant phosphoribosyl pyrophosphate synthetase I (PRPS1)
Regular and Young Investigator Award Abstracts·2025Open Access
Continuous Baseline Microphysical Retrieval (MICROBASE) Value-Added Product Report
2025Open Access
CTIM-03. PROTEIN CHANGES IN SERIAL CSF SAMPLES REFLECT CAR ACTIVITY, TOXICITY AND DISEASE RESPONSE IN PATIENTS WITH DIPG TREATED ON THE BRAINCHILD03 TRIAL
Neuro-Oncology·2025Open Access
Preclinical efficacy of combinatorial B7-H3 CAR T cells and ONC206 against diffuse intrinsic pontine glioma
2025Open Access
Dissecting the molecular origins of opalescence and phase separation in mAb formulations and their relation to aggregation
2025· 1 citedOpen Access
Efficient and Traceless Aptamer‐Based Serial Selection of Naïve and Early Memory CD8 T Cells for CAR T Cell Therapy
Advanced Healthcare Materials·2025Open Access
Tumor inflammation-associated neurotoxicity in children with diffuse intrinsic pontine glioma receiving B7-H3-targeting CAR T cells on BrainChild-03
Neuro-Oncology Practice·2025· 1 cited
HIF-1α-Mediated Disruption of Cellular Junctions: The Impact of Hypoxia on the Tumor Microenvironment and Invasion
International Journal of Molecular Sciences·2025· 7 citedOpen Access
Low Peripheral Blood Counts and Elevated Proinflammatory Cytokines Signal a Poor CD19 Chimeric Antigen Receptor T-cell Response in Acute Lymphoblastic Leukemia
Transplantation and Cellular Therapy·2025· 2 citedOpen Access
Hif-1a-Mediated Disruption of Cellular Junctions: The Impact of Hypoxia on the Tumor Microenvironment and Invasion
Preprints.org·2025Open Access
Abstract 6400: Preclinical efficacy of combinatorial B7-H3 CAR T cell and ONC206 treatment in DIPG/DMG
Cancer Research·2025
Outcomes of PLAT-02 and PLAT-03: Evaluating CD19 CAR T-Cell Therapy and CD19-expressing T-APC Support in Pediatric B-ALL
Blood·2025· 6 citedOpen Access
Engineered CXCR3-A expression enhances the trafficking and efficacy of intracerebroventricularly delivered B7-H3-targeting CAR T cells against diffuse intrinsic pontine glioma
2025Open Access
Locoregional infusion of EGFR806-CAR T cells for recurrent or refractory pediatric CNS tumors: Results of the completed BrainChild02 phase 1 clinical trial
Neuro-Oncology·2025· 12 citedOpen Access
<i>In Situ</i> Bioconjugation of Synthetic Peptides onto Universal Chimeric Antigen Receptor T Cells for Targeted Cancer Immunotherapies
ACS Nano·2025· 3 cited
DNA Aptamer-Polymer Conjugates for Selective Targeting of Integrin α4β1<sup>+</sup> T-Lineage Cancers
ACS Applied Materials & Interfaces·2025· 2 citedOpen Access
Intracerebroventricular B7-H3-targeting CAR T cells for diffuse intrinsic pontine glioma: a phase 1 trial
Nature Medicine·2025· 88 citedOpen Access
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Frequent Co-authors

Stanley R. Riddell(19), Stephen J. Forman(17), Christine E. Brown(8), Rebecca Gardner(6), Carolina Berger(6), Julie R. Ostberg(6), Olivia Finney(6), Julie R. Park(6), Wen-Chung Chang(6), Andrew Raubitschek(6), Cameron J. Turtle(5), Michael Hudecek(5), Jamie R. Wagner(5), Araceli Naranjo(5), Xiuli Wang(5), Rebecca Gardner(5), Hannah Brakke(5), Brian G. Till(5), Jinjuan Wang(5), Oliver W. Press(5)