Heribert Bohlen

Medicine · Health Sciences

37h-index5.0kcitations113works2.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(29), Lymphoma Diagnosis and Treatment(19), Neuroscience and Neural Engineering(18), Pluripotent Stem Cells Research(17), CAR-T cell therapy research(14)

Publications113 total

Selectively expressed RNA molecules as a versatile tool for functionalized cell targeting
Nature Communications·2025· 2 citedOpen Access
Selectively expressed RNA molecules: a new dimension in functionalized cell targeting
2022· 2 cited
Addendum: Rehnelt et al. Frequency-Dependent Multi-Well Cardiotoxicity Screening Enabled by Optogenetic Stimulation. Int. J. Mol. Sci. 2017, 18, 2634
International Journal of Molecular Sciences·2021· 1 citedOpen Access
High throughput screening in calcium transient assay to assess cardiotoxicity of compounds using hiPSC-derived cardiomyocytes
Journal of Pharmacological and Toxicological Methods·2019· 1 cited
Unblinded: Responses to CiPA 28 compounds in COR.4U cardiomyocytes
Journal of Pharmacological and Toxicological Methods·2018
Opening the molecular toolbox: Co-transfection of KCNJ2 and channelrhodopsin 2 mRNAs for precise control of IPS cardiomyocyte pacing and functionality
Journal of Pharmacological and Toxicological Methods·2018
Synchronized electromechanical integration recording of cardiomyocytes
Biosensors and Bioelectronics·2018· 49 cited
Frequency-Dependent Multi-Well Cardiotoxicity Screening Enabled by Optogenetic Stimulation
International Journal of Molecular Sciences·2017· 28 citedOpen Access
Human iPS Cardiomyocytes with Genetically-encoded, Fluorescent Ca2 +, Voltage and cAMP Sensors Reveal Novel Kinetics Around cAMP Signaling: Implications for Drug Safety Screening
Journal of Pharmacological and Toxicological Methods·2017
Impedance-Based Assessment of Preclinical Cardiac Structural Toxicity Using Human iPSC-Derived Cardiomyocytes and its Correlation to In Vivo (dog) Exposures
Journal of Pharmacological and Toxicological Methods·2017
An impedance-based approach using human iPSC-derived cardiomyocytes significantly improves in vitro prediction of in vivo cardiotox liabilities
Toxicology and Applied Pharmacology·2017· 34 cited
Human iPSC derived neurons recorded by MEA technology: A powerful tool for functional assessment of in vitro neurotoxicity and network activity
Journal of Pharmacological and Toxicological Methods·2017· 1 cited
Human iPSC-derived cardiomyocytes for HTS to assess acute drug-induced as well as chronic (TKI) cardiotoxicity
Journal of Pharmacological and Toxicological Methods·2017
Human iPS-derived cardiac myocyte-fibroblast 3D co-cultures: A predictive in vitro model to assess drug-induced contractile and metabolic liabilities
Journal of Pharmacological and Toxicological Methods·2016
Human iPSC-derived cardiomyocytes for HTS to assess acute as well as chronic drug-induced cardiotoxicity
Toxicology Letters·2016
Progressive multifokale Leukenzephalopathie
DMW - Deutsche Medizinische Wochenschrift·2015· 2 citedOpen Access
Human cardiomyocytes derived from iPS cells: Characterization and assessment of drug-induced changes on action potentials, ion currents, extracellular field potentials and impedance signals
Journal of Pharmacological and Toxicological Methods·2014
Minimized Cell Usage for Stem Cell-Derived and Primary Cells on an Automated Patch Clamp System
Biophysical Journal·2014· 38 citedOpen Access
Investigation of Mitochondrial Toxicity in Stem Cell-Derived Cardiomyocytes
2014
In vitro pharmacology and safety testing using human iPS-derived Cor.4U cardiomyocytes
Journal of Pharmacological and Toxicological Methods·2013· 1 cited
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Frequent Co-authors

Volker Diehl(25), Hans Tesch(16), Oliver Manzke(13), Ralf Kettenhofen(9), Bernd K. Fleischmann(8), Eugen Kolossov(6), Martin R. Weihrauch(6), Andreas Engert(6), Dieter Kube(5), Gisela Schön(5), Juergen Hescheler(4), Juergen Wolf(4), Wilhelm Roell(3), Ying Xia(3), Armin Welz(3), Wilhelm Bloch(3), Daniel Ré(3), Sascha Ansén(3), Jürgen Wolf(3), Sandra Titzer(3)