Francesco Fiorentino

Roma Tre University — Italy

Medicine · Health Sciences

21h-index1.5kcitations76works5.82yr avg
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Research Topics

Sirtuins and Resveratrol in Medicine(9), Histone Deacetylase Inhibitors Research(7), Autophagy in Disease and Therapy(6), Protein Degradation and Inhibitors(6), Calcium signaling and nucleotide metabolism(6)

Publications75 total

Structural snapshots of Pseudomonas aeruginosa LptB2FG and LptB2FGC reveal insights into lipopolysaccharide recognition and transport
Nature Communications·2025Open Access
Structural characterisation of the fungal Pmt4 homodimer
Nature Communications·2025Open Access
Quinoline-Based DNA Methyltransferase Inhibitors Featuring Basic Side Chains: Design, Synthesis, and Insight in Biochemical and Anticancer Cell Properties
Journal of Medicinal Chemistry·2025Open Access
Sirtuin modulators: a review of patents from 2020 to 2024
Expert Opinion on Therapeutic Patents·2025· 2 cited
A C <sub>3</sub> ‐Symmetric Diphenylethylendiamine‐Based Catalyst in the Asymmetric Michael Addition of α,β‐Unsaturated Ketones with 4‐Hydroxycoumarin and 4‐Hydroxyquinolin‐2‐One
European Journal of Organic Chemistry·2025Open Access
One-Year Prognostic Differences and Management Strategies between ST-Elevation and Non-ST-Elevation Myocardial Infarction: Insights from the PRAISE Registry
American Journal of Cardiovascular Drugs·2025· 16 cited
Optimization of Lipoplexes Functionalized with a Sialic Acid Mimetic (F9-PEG) to Target the C1858T PTPN22 Variant for Preclinical Assessment of a Novel Immunotherapy in Endocrine Autoimmunity
Pharmaceutics·2025Open Access
Development of C646‐Based Proteolysis Targeting Chimeras Degraders of the Lysine Acetyltransferases CBP and p300
ChemMedChem·2025· 1 citedOpen Access
Native mass spectrometry for proximity-inducing compounds: a new opportunity for studying chemical-induced protein modulation
Expert Opinion on Drug Discovery·2025· 2 cited
Optimization of Lipoplexes Functionalized with a Sialic Acid Mimetic (F9-PEG) to Target the C1858T PTPN22 Variant for Preclinical Assessment of a Novel Immunotherapy in Endocrine Autoimmunity
Preprints.org·2025· 2 citedOpen Access
An Amazing 30-Year Journey around the DABO Family: A Medicinal Chemistry Lesson on a Versatile Class of Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors
Journal of Medicinal Chemistry·2025· 1 citedOpen Access
Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor
Journal of Medicinal Chemistry·2025· 5 citedOpen Access
GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis
Brain Behavior and Immunity·2024· 4 citedOpen Access
Activation and inhibition of sirtuins: From bench to bedside
Medicinal Research Reviews·2024· 16 citedOpen Access
Transmission-Blocking Strategies for Malaria Eradication: Recent Advances in Small-Molecule Drug Development
Pharmaceuticals·2024· 5 citedOpen Access
m6A modification inhibits miRNAs’ intracellular function, favoring their extracellular export for intercellular communication
Cell Reports·2024· 32 citedOpen Access
(Heteroarylmethyl)benzoic Acids as a New Class of Bacterial Cystathionine γ-Lyase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modeling
ACS Infectious Diseases·2024· 2 cited
A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection
PLoS Biology·2024· 5 citedOpen Access
Detergents with Scalable Properties Identify Noncanonical Lipopolysaccharide Binding to Bacterial Inner Membrane Proteins
Journal of the American Chemical Society·2024· 9 citedOpen Access
Uracil‐ and Pyridine‐Containing HDAC Inhibitors Displayed Cytotoxicity in Colorectal and Glioblastoma Cancer Stem Cells
ChemMedChem·2024· 9 cited
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Frequent Co-authors

Dante Rotili(28), Antonello Mai(27), Carol V. Robinson(10), Jani Reddy Bolla(8), Martina Menna(7), Emanuele Fabbrizi(4), Denis Shutin(4), Annamaria Biroccio(3), Sérgio Valente(3), Phillip J. Stansfeld(3), Francesca D’Acunzo(3), Leonhard H. Urner(3), Stefano Tomassi(3), Barbara Benassi(2), Gabriella Zupi(2), Vincenzo Carafa(2), Lucia Altucci(2), Joshua B. Sauer(2), Shahid Mehmood(2), Tarick J. El‐Baba(2)