Kacey VanderVorst

UC Davis Comprehensive Cancer Center

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index611citations22works0.02yr avg
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Research Topics

Wnt/β-catenin signaling in development and cancer(7), Hippo pathway signaling and YAP/TAZ(6), Cancer Cells and Metastasis(4), Cellular Mechanics and Interactions(3), Cancer, Hypoxia, and Metabolism(3)

Publications22 total

A complex of Wnt/planar cell polarity signaling components Vangl1 and Fzd7 drives glioblastoma multiforme malignant properties
Cancer Letters·2023· 13 citedOpen Access
Vangl-dependent Wnt/planar cell polarity signaling mediates collective breast carcinoma motility and distant metastasis
Breast Cancer Research·2023· 24 citedOpen Access
Cellular transformation promotes the incorporation of docosahexaenoic acid into the endolysosome-specific lipid bis(monoacylglycerol)phosphate in breast cancer
Cancer Letters·2023· 6 citedOpen Access
Vangl as a Master Scaffold for Wnt/Planar Cell Polarity Signaling in Development and Disease
Frontiers in Cell and Developmental Biology·2022· 36 citedOpen Access
The Cationic Amphiphilic Drug Hexamethylene Amiloride Eradicates Bulk Breast Cancer Cells and Therapy-Resistant Subpopulations with Similar Efficiencies
Cancers·2022· 6 citedOpen Access
Wnt/PCP signaling mediates breast cancer metastasis by promoting pro-invasive protrusion formation in collectively motile leader cells
2022· 3 citedOpen Access
The Cationic Amphiphilic Drug Hexamethylene Amiloride Eradicates Bulk Breast Cancer Cells and Therapy-Resistant Subpopulations With Similar Efficiencies
Preprints.org·2022· 1 citedOpen Access
Wnt/PCP Signaling Contribution to Carcinoma Collective Cell Migration and Metastasis
Cancer Research·2019· 156 cited
Otubain 1: a non-canonical deubiquitinase with an emerging role in cancer
Endocrine Related Cancer·2018· 89 citedOpen Access
Cellular and molecular mechanisms underlying planar cell polarity pathway contributions to cancer malignancy
Seminars in Cell and Developmental Biology·2018· 91 cited
Profiling Bis(monoacylglycero)phosphate Lipids in Cancer Cell Lysosomes as Therapeutic Targets
The FASEB Journal·2018
Membrane Mucin Muc4 promotes blood cell association with tumor cells and mediates efficient metastasis in a mouse model of breast cancer
Oncogene·2017· 68 citedOpen Access
Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
eLife·2017· 20 citedOpen Access
Author response: Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
2017Open Access
Suppression of planar cell polarity signaling and migration in glioblastoma by Nrdp1-mediated Dvl polyubiquitination
Oncogene·2017· 61 cited
Production of 2HG from wild-type or R172K mutant IDH2 transfected cells
OSF Preprints (OSF Preprints)·2017Open Access
Assessing 2HG levels in AML patient samples
OSF Preprints (OSF Preprints)·2017Open Access
Plasmid quality control data
OSF Preprints (OSF Preprints)·2017Open Access
Assessing the isocitrate-dependent NADPH production and alpha-ketoglutarate-dependent NADPH consumption of wild-type or R172K mutant IDH2
OSF Preprints (OSF Preprints)·2017Open Access
Hexamethylene amiloride engages a novel reactive oxygen species- and lysosome-dependent programmed necrotic mechanism to selectively target breast cancer cells
Cancer Letters·2016· 35 citedOpen Access
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Frequent Co-authors

Kermit L. Carraway(21), Jason Hatakeyama(14), Anastasia L. Berg(9), Megan R. Showalter(9), Oliver Fiehn(9), Tomáš Čajka(8), Courtney A. Dreyer(7), Ashley Rowson-Hodel(5), Elizabeth Iorns(4), Alexandria Denis(4), Nicole Perfito(4), Timothy M. Errington(4), Hyun Lee(3), Matthew Saldana(3), Jessica H. Wald(3), Colleen Sweeney(3), George R. R. Bell(3), Sean R. Collins(3), Michelle Hu(3), Madelyn R. Wheeler(3)