Ara G. Hovanessian

Délégation Paris 5 — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

70h-index15.5kcitations227works0.02yr avg
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Research Topics

RNA regulation and disease(54), HIV Research and Treatment(51), RNA and protein synthesis mechanisms(44), interferon and immune responses(34), RNA Research and Splicing(28)

Publications227 total

Vaccination with the Conserved Caveolin-1 Binding Motif in Human Immunodeficiency Virus Type 1 Glycoprotein gp41 Delays the Onset of Viral Infection and Provides Partial Protection in Simian/Human Immunodeficiency Virus-Challenged Cynomolgus Macaques
Journal of Virology·2018· 1 citedOpen Access
The achilles heel in HIV-1: The conserved caveolin-1 binding domain in the transmembrane envelope glycoprotein gp41 is a B- and T-cell epitope target for vaccine development
Journal of Vaccines & Vaccination·2013
Effi cacy of a mixture of synthetic peptides overlapping the conserved CBD1 epitope in gp41 of HIV- 1 to protect against SHIV162P3 rectal challenge in cynomolgus macaques
Journal of Vaccines & Vaccination·2013
Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type
BMC Cancer·2011· 61 citedOpen Access
Surface Expressed Nucleolin Is Constantly Induced in Tumor Cells to Mediate Calcium-Dependent Ligand Internalization
PLoS ONE·2010· 199 citedOpen Access
Suppression of tumorigenicity of rhabdoid tumor derived G401 cells by the multivalent HB-19 pseudopeptide that targets surface nucleolin
Biochimie·2010· 32 cited
Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice
BMC Cancer·2010· 44 citedOpen Access
The caveolin-1 binding domain of HIV-1 glycoprotein gp41 (CBD1) contains several overlapping neutralizing epitopes
Vaccine·2009· 10 cited
The CBD1 peptide corresponding to the caveolin-1 binding domain of HIV-1 glycoprotein gp41 elicits neutralizing antibodies in cynomolgus macaques when administered with the tetanus T helper epitope
Molecular Immunology·2008· 14 cited
The cell surface expressed nucleolin is a glycoprotein that triggers calcium entry into mammalian cells
Experimental Cell Research·2008· 82 cited
Suppression of Tumor Growth and Angiogenesis by a Specific Antagonist of the Cell-Surface Expressed Nucleolin
PLoS ONE·2008· 138 citedOpen Access
A novel receptor – ligand pathway for entry of Francisella tularensis in monocyte-like THP-1 cells: interaction between surface nucleolin and bacterial elongation factor Tu
BMC Microbiology·2008· 95 citedOpen Access
The immunogenic CBD1 peptide corresponding to the caveolin-1 binding domain in HIV-1 envelope gp41 has the capacity to penetrate the cell membrane and bind caveolin-1
Molecular Immunology·2007· 13 cited
On the discovery of interferon-inducible, double-stranded RNA activated enzymes: The 2′–5′oligoadenylate synthetases and the protein kinase PKR
Cytokine & Growth Factor Reviews·2007· 133 cited
The human 2′-5′oligoadenylate synthetase family: Unique interferon-inducible enzymes catalyzing 2′-5′ instead of 3′-5′ phosphodiester bond formation
Biochimie·2007· 203 cited
HIV-1 neutralizing antibodies elicited by the candidate CBD1 epitope vaccine react with the conserved caveolin-1 binding motif of viral glycoprotein gp41
Journal of Pharmacy and Pharmacology·2006· 8 citedOpen Access
Midkine, a cytokine that inhibits HIV infection by binding to the cell surface expressed nucleolin
Cell Research·2006· 83 citedOpen Access
Pleiotrophin inhibits HIV infection by binding the cell surface‐expressed nucleolin
FEBS Journal·2005· 90 citedOpen Access
Regulatory Serine Residues Mediate Phosphorylation-dependent and Phosphorylation-independent Activation of Interferon Regulatory Factor 7
Journal of Biological Chemistry·2005· 70 citedOpen Access
The Caveolin-1 Binding Domain of HIV-1 Glycoprotein gp41 Is an Efficient B Cell Epitope Vaccine Candidate against Virus Infection
Immunity·2004· 63 citedOpen Access
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Frequent Co-authors

Michael G. Katze(11), J Galabru(10), Éliane Meurs(8), Bernard Krust(8), Ian M. Kerr(6), Bryan Williams(6), Josette Svab(5), Karen L. Chong(4), Luc Montagnier(4), Glen N. Barber(3), Ronald E. Brown(3), A.G. Laurent-Crawford(3), B Safer(3), Joseph T. Tomita(3), John N. Wood(3), Michael J. Clemens(2), Sylviane Muller(2), Yves Rivière(2), Marie-Anne Rey-Cuillé(2), Suzanne Kadereit(2)