Christian J. Janzen

University of Würzburg — Germany

Medicine · Health Sciences

26h-index2.9kcitations58works1.92yr avg
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Research Topics

Trypanosoma species research and implications(43), Research on Leishmaniasis Studies(18), Insect symbiosis and bacterial influences(10), Biochemical and Molecular Research(10), Signaling Pathways in Disease(8)

Publications58 total

Quantitative proteomics of infected macrophages reveals novel Leishmania virulence factors
PLoS Pathogens·2026Open Access
A Leishmania virulence factor harnesses an allosteric kinase switch to regulate its ubiquitin ligase activity
Molecular Cell·2025· 1 citedOpen Access
The histone methyltransferase DOT1B is dispensable for stage differentiation and macrophage infection of Leishmania mexicana
Frontiers in Cellular and Infection Microbiology·2025· 3 citedOpen Access
Quantitative proteomics of infected macrophages reveals novel <i>Leishmania</i> virulence factors
2025· 2 citedOpen Access
TelAP2 links TelAP1 to the telomere complex in Trypanosoma brucei
Scientific Reports·2024· 4 citedOpen Access
The histone methyltransferase DOT1B is dispensable for stage differentiation and macrophage infection in <i>Leishmania mexicana</i>
2024· 2 citedOpen Access
TelAP2 links TelAP1 to the telomere complex in <i>Trypanosoma brucei</i>
2024· 1 citedOpen Access
Characterisation of TbSmee1 suggests endocytosis allows surface-bound cargo to enter the trypanosome flagellar pocket
Journal of Cell Science·2023· 2 citedOpen Access
Author Reply to Peer Reviews of Characterisation of TbSmee1 indicates that endocytosis is required for access of surface-bound cargo to the trypanosome flagellar pocket
2023
A novel SNF2 ATPase complex in Trypanosoma brucei with a role in H2A.Z-mediated chromatin remodelling
PLoS Pathogens·2022· 18 citedOpen Access
Characterisation of TbSmee1 indicates that endocytosis is required for access of surface-bound cargo to the trypanosome flagellar pocket
2022· 1 citedOpen Access
Quantification of RNA Polymerase I transcriptional attenuation at the active VSG expression site in <i>Trypanosoma brucei</i>
2021· 2 citedOpen Access
A novel SNF2 ATPase complex in <i>Trypanosoma brucei</i> with a role in H2A.Z-mediated chromatin remodelling
2021· 3 citedOpen Access
Genome maintenance functions of a putative Trypanosoma brucei translesion DNA polymerase include telomere association and a role in antigenic variation
Nucleic Acids Research·2020· 20 citedOpen Access
Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei
PLoS Biology·2020· 44 citedOpen Access
Trimethylation of histone H3K76 by Dot1B enhances cell cycle progression after mitosis in Trypanosoma cruzi
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2020· 15 cited
A DOT1B/Ribonuclease H2 protein complex is involved in R-loop processing, genomic integrity and antigenic variation in <i>Trypanosoma brucei</i>
2020· 2 citedOpen Access
Genome maintenance functions of <i>Trypanosoma brucei</i> DNA Polymerase N include telomere association and a role in antigenic variation
2019Open Access
Genome organization and DNA accessibility control antigenic variation in trypanosomes
Nature·2018· 216 citedOpen Access
TelAP1 links telomere complexes with developmental expression site silencing in African trypanosomes
Nucleic Acids Research·2018· 30 citedOpen Access
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Frequent Co-authors

Falk Butter(14), George Cross(10), Sandra B. Hake(6), Otto Haller(5), Mario Dejung(4), Susanne Krämer(4), Nicole Eisenhuth(4), Georg Kochs(3), T. Nicolai Siegel(3), Luísa M. Figueiredo(3), Ferdinand Bucerius(3), G. Dindar(3), Markus Engstler(3), Sérgio Schenkman(3), Helena Reis(3), Nadine Weisert(3), Tim Vellmer(3), Laura Hartleb(3), Albert Fradera-Sola(3), Elisabeth Meyer-Natus(3)