Xiaoyu Ai

Nankai University — China

Materials Science · Physical Sciences

14h-index973citations57works1.52yr avg
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Research Topics

Nanoparticle-Based Drug Delivery(9), Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis(8), Quantum Information and Cryptography(5), Nanoplatforms for cancer theranostics(5), Advanced Drug Delivery Systems(5)

Publications56 total

A magnetic nanoparticles-based ligand fishing method coupled with parallel artificial membrane permeability assay for rapid discovery and analysis of GSNO reductase inhibitors with good membrane permeability from Salvia miltiorrhiza Bunge
International Journal of Biological Macromolecules·2025
Intratracheal instillation of chitosan-coated formononetin-loaded porous microspheres prolongs lung retention and improves the treatment in bleomycin-induced pulmonary fibrosis
European Journal of Pharmaceutical Sciences·2025Open Access
The Genetic and Embryo–Fetal Developmental Toxicity Profile of the Novel Transgelin Agonist Deg-AZM: Ames, Micronucleus, Chromosomal Aberration, and Rat EFD Studies
Biomedicines·2025Open Access
Preclinical Safety Profile of Deg-AZM, a Clinical-Stage New Transgelin Agonist: hERG Inhibition Study In Vitro, Cardiovascular–Respiratory Pharmacology, and Single/Repeated-Dose Toxicity in Beagle Dogs
Biomedicines·2025· 1 citedOpen Access
Author Correction: Daidzein alleviates skin fibrosis by suppressing TGF-β1 signaling pathway via targeting PKM2
Scientific Reports·2025Open Access
Pirfenidone Lung Distribution is Amplified in Idiopathic Pulmonary Fibrosis: Critical roles of tight junction disruption and drug transporter dysregulation
2025Open Access
Transplacental transfer of metformin and interaction of metformin with the uptake transporters of placental trophoblast cells
European Journal of Pharmaceutical Sciences·2025· 1 citedOpen Access
Bergenin and vitexin delivery platform using mouse lung fibroblasts-derived exosomes for bleomycin-induced pulmonary fibrosis therapy
International Journal of Pharmaceutics·2025· 3 cited
Deglycosylated azithromycin alleviates cisplatin-evoked constipation in mice by altering host metabolome and gut microbiota composition
Frontiers in Microbiology·2025Open Access
Formononetin-Loaded PLGA Large Porous Microparticles via Intratracheal Instillation for Bleomycin-Induced Pulmonary Fibrosis Treatment
AAPS PharmSciTech·2025· 8 cited
Treatment of Bleomycin-induced Pulmonary Fibrosis by Intratracheal Instillation Administration of Ellagic Acid-Loaded Chitosan Nanoparticles
AAPS PharmSciTech·2025· 1 cited
Daidzein alleviates skin fibrosis by suppressing TGF-β1 signaling pathway via targeting PKM2
Scientific Reports·2025· 3 citedOpen Access
Macrophage membrane entrapped rapamycin-loaded TPGS/F127 micelles through intratracheal instillation for enhanced drug delivery and therapy to lung cancer with pulmonary fibrosis
International Journal of Pharmaceutics·2025
The in vivo metabolic pathway of Deg-AZM and in vitro investigations into the contribution of drug metabolizing enzymes and drug transporters in the drug interactions of Deg-AZM, a clinical-stage new transgelin agonist
Frontiers in Pharmacology·2025· 1 citedOpen Access
Zanubrutinib ameliorates experimental idiopathic inflammatory myopathy-associated interstitial lung disease by BTK/NF-κB signaling pathway
International Immunopharmacology·2024· 2 cited
PK-PD relationship of poorly absorbable active ingredients from traditional Chinese medicines explaining by metabolic enzyme of gut microbiota: A case study of Dehydrocorydaline
Journal of Pharmaceutical and Biomedical Analysis·2024· 2 cited
Preclinical pharmacokinetic studies and prediction of human PK profiles for Deg-AZM, a clinical-stage new transgelin agonist
Frontiers in Pharmacology·2024· 1 citedOpen Access
Remdesivir alleviates skin fibrosis by suppressing TGF-β1 signaling pathway
PLoS ONE·2024· 4 citedOpen Access
A rearranged abietane diterpenoid from Clerodendrum mandarinorum inhibits tumor progression of oral squamous cell carcinoma in vitro
Arabian Journal of Chemistry·2024Open Access
Epidemiological investigation of sex hormones and their metabolism-related gene single nucleotide polymorphisms in patients with benign prostatic hyperplasia complicated with late-onset hypogonadism: a retrospective cohort study
International Journal of Surgery·2024· 5 citedOpen Access
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Frequent Co-authors

Honggang Zhou(14), Cheng Yang(13), Jin Sun(10), Xiang Xu(9), Zhonggui He(8), Chunnuan Wu(7), Hongting Liu(7), Yao Sun(7), Honggang Zhou(6), Xiaoting Gu(6), He Lian(5), Shuang Chen(5), Tao Sun(5), Zhonggui He(5), Wenqi Li(5), Xiaohe Li(5), Conglu Zhao(5), Keran Li(5), Xiaohe Li(5), Yongjun Wang(4)