Ruili Huang

National Institutes of Health — United States

Computer Science · Physical Sciences

58h-index13.5kcitations314works3.82yr avg
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Research Topics

Computational Drug Discovery Methods(112), Pharmacogenetics and Drug Metabolism(32), Animal testing and alternatives(28), Estrogen and related hormone effects(24), Metabolomics and Mass Spectrometry Studies(21)

Publications314 total

Identifying androgen receptor antagonists using a metabolically competent high-throughput screening assay
Current Research in Toxicology·2025Open Access
Application of Transcription Factor Decoys for Avermectin and Lycopene Overproduction in <i>Streptomyces avermitilis</i>
Journal of Agricultural and Food Chemistry·2025
Systematic evaluation of Tox21 compounds that target β-adrenergic receptors and their role in cardiotoxicity
Toxicology and Applied Pharmacology·2025Open Access
Development of an endogenous quorum-sensing based bifunctional dynamic regulation system for efficient product synthesis in Streptomyces
Bioresource Technology·2025· 1 cited
MT1G activation in dopaminergic neurons identifies chelators and their relationships to cytotoxicity
SLAS DISCOVERY·2025· 2 citedOpen Access
Leveraging viral genome sequences and machine learning models for identification of potentially selective antiviral agents
Communications Chemistry·2025Open Access
Expanded Tox21 biological assay panel for the prediction of drug-induced liver injury and cardiotoxicity
Environmental Health Perspectives·2025Open Access
ICRF193 potentiates the genotoxicity of etoposide
Scientific Reports·2025Open Access
The threshold effect of fasting blood glucose levels on the risk of delivering macrosomia in gestational diabetes mellitus patients
Frontiers in Endocrinology·2025Open Access
Profiling the Tox21 Compound Library for Their Inhibitory Effects on Cytochrome P450 Enzymes
International Journal of Molecular Sciences·2025· 4 citedOpen Access
Application of cytochrome P450 enzyme assays to predict p53 inducers and AChE inhibitors that require metabolic activation
Toxicology and Applied Pharmacology·2025· 2 cited
Profiling of Environmental Mixtures Containing Metals for Their Toxicity Pathways and Mechanism of Action
Environmental Science & Technology·2025· 9 cited
Investigating blood–brain barrier penetration and neurotoxicity of natural products for central nervous system drug development
Scientific Reports·2025· 10 citedOpen Access
Lessons learned from evaluating defined chemical mixtures in a high-throughput estrogen receptor assay system
Toxicological Sciences·2025· 1 citedOpen Access
Systematic identification of cancer pathways and potential drugs for intervention through multi-omics analysis
The Pharmacogenomics Journal·2025· 2 citedOpen Access
Genetic Variants of <i>GBP4</i>: Reduced Risks for Drug‐Induced Acute Liver Failure in Non‐Finnish European Population
Liver International·2025· 1 citedOpen Access
Analytical Quality Evaluation of the Tox21 Compound Library
Chemical Research in Toxicology·2024· 8 citedOpen Access
Identification of human pregnane X receptor antagonists utilizing a high-throughput screening platform
Frontiers in Pharmacology·2024· 2 citedOpen Access
Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data
Cell Genomics·2024· 3 citedOpen Access
Evaluating the Utility of the MSTI Assay in Predicting Compound Promiscuity and Cytotoxicity
Chemical Research in Toxicology·2024
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Frequent Co-authors

Menghang Xia(32), Christopher P. Austin(25), Srilatha Sakamuru(15), Anton Simeonov(14), Richard Judson(12), Keith A. Houck(12), Raymond R. Tice(12), Paul Shinn(11), Noel Southall(8), Ann M. Richard(7), Daniel M. Rotroff(7), Wei Zheng(6), Ðắc-Trung Nguyễn(6), Tongan Zhao(6), Thomas B. Knudsen(6), Kevin M. Crofton(6), Russell S. Thomas(6), James Inglese(6), Kristine L. Witt(6), Matias S. Attene‐Ramos(6)