Phillip R. Lazzara

University of Illinois Chicago — United States

Chemistry · Physical Sciences

8h-index280citations17works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Chemical Synthesis and Reactions(4), Asymmetric Hydrogenation and Catalysis(3), Genomics, phytochemicals, and oxidative stress(3), Synthesis and Biological Evaluation(3), Synthesis and biological activity(2)

Publications17 total

A Small Molecule Coordinates Symbiotic Behaviors in a Host Organ
mBio·2021· 26 citedOpen Access
Discovery of a microbially produced small molecule in a host-specific organ
2020Open Access
Synthesis and Evaluation of Noncovalent Naphthalene-Based KEAP1-NRF2 Inhibitors
ACS Medicinal Chemistry Letters·2020· 25 citedOpen Access
Scaffold-hopping as a strategy to address metabolic liabilities of aromatic compounds
RSC Medicinal Chemistry·2019· 63 citedOpen Access
Crystal structure of N-[(4-methoxyphenyl)sulfonyl]-N-(4-{[(4-methoxyphenyl)sulfonyl]amino}naphthalen-1-yl)glycine bound to human Keap1 Kelch domain
2019
Isoquinoline Kelch-like ECH-Associated Protein 1-Nuclear Factor (Erythroid-Derived 2)-like 2 (KEAP1-NRF2) Inhibitors with High Metabolic Stability
Journal of Medicinal Chemistry·2019· 49 citedOpen Access
Crystal structure of N-(4-((4-methoxy-N-(2,2,2-trifluoroethyl)phenyl)sulfonamido)isoquinolin-1-yl)-N-((4-methoxyphenyl)sulfonyl)glycine bound to human Keap1 Kelch domain
2019
Steroid receptor/coactivator binding inhibitors: An update
Molecular and Cellular Endocrinology·2019· 37 citedOpen Access
Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear Factor (Erythroid-derived 2)-like 2 (NRF2) Inhibitors
Journal of Medicinal Chemistry·2018· 49 citedOpen Access
Heterocycles Via the PD-Catalyzed Heterofunctionalization of Alkylidenecyclopropanes
Loyola eCommons (Loyola University Chicago)·2017Open Access
CCDC 1500563: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
CCDC 1500564: Experimental Crystal Structure Determination
The Cambridge Structural Database·2017Open Access
Pd‐Catalyzed Carboamination of Alkylidenecyclopropanes: Synthesis of Congested Pyrrolidines and Piperidines
Chemistry - A European Journal·2016· 15 cited
ChemInform Abstract: Iron(III) Tosylate Catalyzed Deprotection of Aromatic Acetals in Water.
ChemInform·2010
Iron(III) tosylate-catalyzed deprotection of aromatic acetals in water
Tetrahedron Letters·2010· 16 cited
Iron (III) Tosylate Catalyzed Synthesis of 1,1 Diesters (Acylals) From Aldehydes
2010
Iron (III) Tosylate Catalyzed Deprotection of Cyclic Acetals
2010

Frequent Co-authors

Terry W. Moore(7), Brian P. David(4), Katherine Dye(4), Kiira Ratia(4), Benjamin G. Richardson(3), Kornelia J. Skowron(3), Zamia Siddiqui(3), Margaret E. Olson(3), Michael V. Chiodo(3), Keegan P. Fitzpatrick(3), Chad C. Eichman(3), Atul D. Jain(2), Sekhar P. Reddy(2), Katherine E. Zink(2), Mark J. Mandel(2), Laura M. Sanchez(2), James P. Carolan(2), Ram S. Mohan(2), Faculty Advisor Mohan(2), B.P. David(2)