Renate Griffith

University of Tasmania — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index2.4kcitations123works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(17), X-ray Diffraction in Crystallography(14), Crystallization and Solubility Studies(11), Antibiotic Resistance in Bacteria(10), Synthesis and biological activity(9)

Publications123 total

Q1291H-CFTR molecular dynamics simulations and ex vivo theratyping in nasal epithelial models and clinical response to elexacaftor/tezacaftor/ivacaftor in a Q1291H/F508del patient
Frontiers in Molecular Biosciences·2023· 4 citedOpen Access
Development of Potential Inhibitors for Human T-lymphotropic VirusType I Integrase Enzyme: A Molecular Modeling Approach
Current Computer - Aided Drug Design·2023· 1 cited
Computational Evaluation of N-Based Transannular Interactions in Some Model Fused Medium-Sized Heterocyclic Systems and Implications for Drug Design
Molecules·2023· 4 citedOpen Access
S945L-CFTR molecular dynamics, functional characterization and tezacaftor/ivacaftor efficacy in vivo and in vitro in matched pediatric patient-derived cell models
Frontiers in Pediatrics·2022· 7 citedOpen Access
Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity
iScience·2021· 13 citedOpen Access
<i>In silico</i> and functional characterisation of an ultra-rare <i>CFTR</i> mutation identifies novel lasso motif interactions regulating channel gating
2021Open Access
Density functional theory assessment of transannular N⋯Y interactions in some medium-sized heterocycles
Computational and Theoretical Chemistry·2021· 2 cited
Inhibitors of bacterial RNA polymerase transcription complex
Bioorganic Chemistry·2021· 6 cited
Molecular dynamics and theratyping in airway and gut organoids reveal R352Q-CFTR conductance defect
2021· 3 citedOpen Access
Discovery of neuroprotective agents that inhibit human prolyl hydroxylase PHD2
Bioorganic & Medicinal Chemistry·2021· 8 citedOpen Access
Application of Molecular Docking for the Development of Improved HIV-1 Reverse Transcriptase Inhibitors
Current Computer - Aided Drug Design·2020· 1 cited
CCDC 1552252: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
CCDC 1552250: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
Exploration of the Differences between Amine and Thiolate Addition to Acetylenedicarboxylates
The Journal of Organic Chemistry·2019
Dihydropyrrolones as bacterial quorum sensing inhibitors
Bioorganic & Medicinal Chemistry Letters·2019· 30 cited
Tuning the properties of a cyclic RGD-containing tetrapeptide through backbone fluorination
Organic & Biomolecular Chemistry·2018· 11 citedOpen Access
In silico Analysis of FtsZ Crystal Structures Towards a New Target for Antibiotics
Australian Journal of Chemistry·2018· 9 cited
Molecular targeting for treatment of human T-lymphotropic virus type 1 infection
Biomedicine & Pharmacotherapy·2018· 34 citedOpen Access
Design and Synthesis of Lactams Derived from Mucochloric and Mucobromic Acids as Pseudomonas aeruginosa Quorum Sensing Inhibitors
Molecules·2018· 23 citedOpen Access
How is residence time modulated? Identification of the orthosteric vestibule and allosteric binding sites of the α&lt;sub&gt;1A&lt;/sub&gt; and β&lt;sub&gt;2&lt;/sub&gt; adrenoceptors
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2018Open Access
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Frequent Co-authors

Naresh Kumar(11), David StC. Black(10), Peter J. Lewis(6), Paul A. Keller(6), Leonie K. Ashman(5), Cong Ma(5), Stuart A. Rice(5), Stephen G. Pyne(4), John B. Bremner(4), Xiao Yang(4), Hakan Kandemir(4), Marcin Mielczarek(4), Nripendra Nath Biswas(4), Samuel K. Kutty(4), George M. Iskander(4), Malgorzata N. Drwal(3), Burak Çoban(3), Mark Willcox(3), Scott P. Leach(3), Shashidhar Nizalapur(3)