Chai-Wan Kim

Southwestern Medical Center

Medicine · Health Sciences

17h-index1.5kcitations27works33.52yr avg
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Research Topics

Blood properties and coagulation(13), Erythrocyte Function and Pathophysiology(8), Liver Disease Diagnosis and Treatment(5), Lipid metabolism and biosynthesis(4), Peroxisome Proliferator-Activated Receptors(3)

Publications27 total

Plasma membrane accessible cholesterol is regulated by ACC1 and lipid droplets
2025· 1 citedOpen Access
Reciprocal regulation of cardiac β-oxidation and pyruvate dehydrogenase by insulin
Journal of Biological Chemistry·2024· 6 citedOpen Access
Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability
Cell Metabolism·2024· 51 citedOpen Access
DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER
Cell Metabolism·2024· 76 citedOpen Access
Effect of Knockout of Two Acetyl-CoA Carboxylase Isoforms in the Isolated Mouse Heart on Oxidation of Exogenous and Endogenous Energy Sources
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition·2023
204-OR: Inhibition of Hepatic ACC on a High-Fat Diet Results in Hyperglycemia and Hepatomegaly Due to Excess Energy Generation
Diabetes·2020
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation
Cell Metabolism·2017· 106 cited
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation
Cell Metabolism·2017· 400 citedOpen Access
Doxorubicin Induces the Persistent Activation of Intracellular Transglutaminase 2 That Protects from Cell Death
Molecules and Cells·2012· 22 citedOpen Access
Crystal structure of Spot 14, a modulator of fatty acid synthesis
Proceedings of the National Academy of Sciences·2010· 69 citedOpen Access
Monoclonal Antibodies to Human Transglutaminase 4
Hybridoma·2010· 5 cited
Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis
Proceedings of the National Academy of Sciences·2010· 142 citedOpen Access
Transglutaminase 2 inhibits apoptosis induced by calciumoverload through down-regulation of Bax
Experimental & Molecular Medicine·2010· 60 citedOpen Access
Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis
2010· 4 cited
Differential alternative splicing of human transglutaminase 4 in benign prostate hyperplasia and prostate cancer
Experimental & Molecular Medicine·2010· 28 citedOpen Access
Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-κB activity in hypoxic tumor cells
Oncogene·2009· 126 citedOpen Access
Degradation of transglutaminase 2 by calcium‐mediated ubiquitination responding to high oxidative stress
FEBS Letters·2009· 25 cited
TGFβ mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation
The FASEB Journal·2008· 68 cited
Clinical significance of anti-filaggrin antibody recognizing uncitrullinated filaggrin in rheumatoid arthritis
Experimental & Molecular Medicine·2005· 10 citedOpen Access
Colorimetric transglutaminase assays combined with immunological signal amplification
Analytical Biochemistry·2005· 6 cited
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Frequent Co-authors

Ju‐Hong Jeon(15), Dong‐Myung Shin(13), Sung‐Yup Cho(12), In Gyu Kim(11), Jay D. Horton(9), Kyungho Choi(8), Eui Man Jeong(7), Gi-Yong Jang(7), Shawn C. Burgess(5), Stanisław Deja(4), Xiaorong Fu(4), Young-Ah Moon(3), Hyock Joo Kwon(3), Hye-Jin Lee(3), Joon-Cheol Kwon(3), Carol Addy(2), Jun Kusunoki(2), Norma N. Anderson(2), Li Cai(2), Marcie Ruddy(2)