John W. Tobias

California University of Pennsylvania — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

53h-index13.2kcitations173works4.72yr avg
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Research Topics

RNA modifications and cancer(16), Epigenetics and DNA Methylation(14), MicroRNA in disease regulation(13), Cancer Immunotherapy and Biomarkers(11), Sperm and Testicular Function(10)

Publications172 total

EGFR activation in cholangiocytes promotes extrahepatic bile duct regeneration after injury
Hepatology Communications·2025Open Access
Opposing effects of systemic and pancreas-specific inhibition of BCKDK on pancreatic carcinogenesis
2025Open Access
EGFR activation in cholangiocytes promotes extrahepatic bile duct regeneration after injury
2025· 1 citedOpen Access
Moderate‐ and High‐Speed Treadmill Running Exercise Have Minimal Impact on Rat Achilles Tendon
Journal of Orthopaedic Research®·2024· 2 citedOpen Access
WNT signaling contributes to the extrahepatic bile duct proliferative response to obstruction in mice
JCI Insight·2024· 4 citedOpen Access
Pivotal roles for cancer cell–intrinsic mPGES-1 and autocrine EP4 signaling in suppressing antitumor immunity
JCI Insight·2024· 6 citedOpen Access
Abstract C039: Investigating ER stress responses in pancreatic ductal adenocarcinoma under lipid imbalance
Cancer Research·2024
Diurnal gene expression patterns in retina and choroid distinguish myopia progression from myopia onset
PLoS ONE·2024· 4 citedOpen Access
IL-12 drives the differentiation of human T follicular regulatory cells
Science Immunology·2024· 13 cited
Abstract 4985: Pivotal roles for cancer cell-intrinsic mPGES-1 and autocrine EP4 signaling in suppressing anti-tumor immunity
Cancer Research·2024
Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma
Nature Communications·2024· 25 citedOpen Access
Abstract B051: Investigating lipid homeostasis in pancreatic ductal adenocarcinoma under tumor-like stress
Cancer Research·2024
Abstract B054: Investigating ER stress responses in pancreatic ductal adenocarcinoma under lipid imbalance
Cancer Research·2024
Diurnal retinal and choroidal gene expression patterns support a role for circadian biology in myopia pathogenesis
Scientific Reports·2024· 11 citedOpen Access
Telomeric DNA breaks in human induced pluripotent stem cells trigger ATR-mediated arrest and telomerase-independent telomere damage repair
Journal of Molecular Cell Biology·2023· 5 citedOpen Access
Menin Maintains Cholesterol Content in Colorectal Cancer via Repression of LXR-Mediated Transcription
Cancers·2023· 3 citedOpen Access
Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy
2023· 3 citedOpen Access
FOG2 coding variant Ser657Gly is associated with Coronary Microvascular Disease through altered hypoxia-mediated gene transcription
2023· 2 citedOpen Access
Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice
International Journal of Molecular Sciences·2023· 4 citedOpen Access
Abstract 3276: Tumor cell-intrinsic PGE2-EP4 signaling is a major immunosuppressive pathway in pancreatic cancer
Cancer Research·2023
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Frequent Co-authors

Alexander Varshavsky(6), Andres J. Klein–Szanto(6), Mary R. Avarbock(5), Ralph L. Brinster(5), Xin Wu(4), Donald Baldwin(4), Hiroshi Nakagawa(4), Christopher J. Lengner(4), Warren S. Pear(3), Jon C. Aster(3), Robert H. Vonderheide(3), Don A. Baldwin(3), Shaun M. Goodyear(3), Angela Nakauka‐Ddamba(3), Shane T. Jensen(3), Andreas Bachmair(2), David K. Gonda(2), Carlos G. Rodríguez(2), Hong Sai(2), Jinyang Li(2)