Darwyn Kobasa

Public Health Agency of Canada — Canada

Medicine · Health Sciences

41h-index7.8kcitations175works1.82yr avg
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Research Topics

Influenza Virus Research Studies(62), SARS-CoV-2 and COVID-19 Research(51), Viral Infections and Outbreaks Research(43), Respiratory viral infections research(39), Viral Infections and Vectors(38)

Publications174 total

Immune-focused RBD nanoparticles induce cross-reactive, RBS-directed responses capable of variant-resistant SARS-CoV-2 neutralization
PLoS Pathogens·2026Open Access
Cross-reactive H5N1 Neuraminidase Antibodies by Age and Influenza A Imprinting Cohorts of the Past Century: Population-Based Serosurvey, British Columbia, Canada
The Journal of Infectious Diseases·2026· 1 cited
A VSV-vector vaccine simultaneously targeting H5N1 hemagglutinin (HA) and matrix protein 2 (M2) induces robust neutralizing and ADCC antibody responses and provides full protection against lethal H5N1 infection in a mouse model
2025Open Access
Electroporation and LNP-mediated delivery of plasmid DNA-encoded H5N1 influenza virus hemagglutinin support protection against highly pathogenic avian influenza
npj Vaccines·2025Open Access
Efficacy and potential human and economic impact of a broadly protective betacoronavirus vaccine
2025Open Access
Intranasal vaccine induces broad and long-lasting immunity against the hemagglutinin stem of group 2 influenza A viruses
Antiviral Research·2025Open Access
CD4+ and CD8+ T cells are not the main driver of Lassa fever pathogenesis in macaques
JCI Insight·2025Open Access
Dairy cow- and avian-origin clade 2.3.4.4b H5N1 induce severe mastitis in lactating goats and transmission to suckling goats
Cell Reports·2025· 3 citedOpen Access
Cross-reactive neuraminidase inhibition antibodies against H5N1 by consecutive influenza A imprinting cohorts of the past century: population-based serosurvey, British Columbia, Canada
2025Open Access
Human protein interaction networks of ancestral and variant SARS-CoV-2 in organ-specific cells and bodily fluids
Nature Communications·2025· 3 citedOpen Access
Intramuscular DNA vaccine provides protection in non-human primate and mouse models of SARS-CoV-2
Frontiers in Immunology·2025· 2 citedOpen Access
Digitally Immune-Optimised Next-Generation Influenza Vaccine Provides Cross-Clade Protection Against Emerging H5Nx Viruses
2025Open Access
Highly pathogenic avian influenza H5N1 clade 2.3.4.4b hemagglutinin and/or neuraminidase elicit immunity in a recombinant nanoparticle vaccine
Cell Biomaterials·2025· 3 cited
Transient, early, female-specific increase in cortical glial fibrillary acidic protein distribution in the Syrian hamster model of mild peripheral COVID-19
2025Open Access
Treatment with the CCR5 antagonist OB-002 reduces lung pathology, but does not prevent disease in a Syrian hamster model of SARS-CoV-2 infection
PLoS ONE·2025Open Access
Intranasal Vaccine Induces Broad and Long-Lasting Immunity Against the Hemagglutinin Stem of Group 2 Influenza a Viruses
SSRN Electronic Journal·2025Open Access
Protein Expression Platforms and the Challenges of Viral Antigen Production
Vaccines·2024· 11 citedOpen Access
Dissecting immunological mechanisms underlying influenza viral nucleoprotein-induced mucosal immunity against diverse viral strains
Emerging Microbes & Infections·2024· 5 citedOpen Access
SARS-CoV-2 infection results in a unique lung proteome long after virus resolution in the hamster
npj Viruses·2024· 2 citedOpen Access
Development and characterization of monoclonal antibodies recognizing nucleocapsid protein of multiple SARS-CoV-2 variants
Heliyon·2024· 2 citedOpen Access
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Frequent Co-authors

Yoshihiro Kawaoka(13), Anders Leung(11), Gary Wong(9), Heinz Feldmann(8), Gary Kobinger(8), Jonathan Audet(6), Carissa Embury‐Hyatt(6), Hideki Ebihara(5), Ayato Takada(5), James E. Strong(5), David B. Weiner(5), Charlene Ranadheera(5), Kevin M. Coombs(4), Shihua He(4), Kaylie N. Tran(4), David Safronetz(4), Xiangguo Qiu(4), Steven J.M. Jones(3), Kyoko Shinya(3), Michael G. Katze(3)