Martina P. Pasillas

University of California, San Diego — United States

Immunology and Microbiology · Life Sciences

22h-index5.2kcitations37works4.02yr avg
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Research Topics

Immune cells in cancer(8), Genomics and Chromatin Dynamics(7), Epigenetics and DNA Methylation(7), Acute Myeloid Leukemia Research(6), Liver Disease Diagnosis and Treatment(6)

Publications37 total

Mechanisms driving epigenetic and transcriptional responses of microglia in a neurodegenerative lysosomal storage disorder model
2024· 4 citedOpen Access
Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes
Nature Immunology·2023· 12 citedOpen Access
Human microglia maturation is underpinned by specific gene regulatory networks
Immunity·2023· 51 citedOpen Access
SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity
Nature Immunology·2023· 61 citedOpen Access
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4
Neuron·2022· 103 citedOpen Access
Systematic analysis of transcriptional and epigenetic effects of genetic variation in Kupffer cells enables discrimination of cell intrinsic and environment-dependent mechanisms
2022Open Access
Somatic mosaicism reveals clonal distributions of neocortical development
Nature·2022· 58 citedOpen Access
Heterogeneity of HSCs in a Mouse Model of NASH
Hepatology·2021· 134 citedOpen Access
Somatic mosaicism in the mature brain reveals clonal cellular distributions during cortical development
2020· 16 citedOpen Access
264 Interrogating altered enhancer landscapes to decode pathogenic changes in macrophages during chronic inflammatory disease
Journal of Investigative Dermatology·2020
Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis
Immunity·2020· 408 citedOpen Access
Niche-Specific Re-Programming of Epigenetic Landscapes Drives Myeloid Cell Diversity in NASH
SSRN Electronic Journal·2020· 3 citedOpen Access
Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis
Cell Metabolism·2019· 192 citedOpen Access
Brain cell type–specific enhancer–promoter interactome maps and disease <b>-</b> risk association
Science·2019· 750 citedOpen Access
Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity
Immunity·2019· 399 citedOpen Access
Cell type-specific enhancer-promoter connectivity maps in the human brain and disease risk association
2019· 8 citedOpen Access
Deciphering liver environmental signaling pathways for Kupffer cell identity
The Journal of Immunology·2019
Exploiting altered enhancer landscapes to decode pathogenic changes in gene expression of diverse hepatic macrophages
The Journal of Immunology·2019
Hepatic Myeloid Cell Diversity During Fibrosis and Nonalcoholic Steatohepatitis
The Journal of Immunology·2018
An environment-dependent transcriptional network specifies human microglia identity
Science·2017· 1.3k citedOpen Access
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Frequent Co-authors

Christopher K. Glass(19), Mark P. Kamps(12), Nathanael J. Spann(12), Ty D. Troutman(11), Johannes C. M. Schlachetzki(10), Jason S. Seidman(10), Mashito Sakai(10), Hunter Bennett(8), Cassi M. Bruni(7), Verena M. Link(7), David Gosselin(6), Alexi Nott(6), David B. Sykes(6), Zhengyu Ouyang(6), Kaori M. Ego(6), Nicole G. Coufal(5), Gang Greg Wang(5), Mojgan Hosseini(5), Inge R. Holtman(4), Carolyn O’Connor(4)