Jacob K. Asiedu

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index4.9kcitations15works0.02yr avg
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Research Topics

Bioinformatics and Genomic Networks(8), Computational Drug Discovery Methods(6), Advanced Proteomics Techniques and Applications(4), Biomedical Text Mining and Ontologies(4), Gene expression and cancer classification(3)

Publications15 total

Corrigendum to "Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data".
PubMed·2025Open Access
Abstract 5459: Accelerating the development of biologics: PRISM high throughput screening enables rapid preclinical characterization of antibodies, ADCs and payloads
Cancer Research·2025
Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data
Molecular & Cellular Proteomics·2025Open Access
Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds
Scientific Data·2021· 16 citedOpen Access
The GCTx format and cmap{Py, R, M, J} packages: resources for optimized storage and integrated traversal of annotated dense matrices
Bioinformatics·2018· 54 citedOpen Access
A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations
Cell Systems·2018· 94 citedOpen Access
The GCTx format and cmap{Py, R, M} packages: resources for the optimized storage and integrated traversal of dense matrices of data and annotations
2017· 12 citedOpen Access
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles
Cell·2017· 3.5k citedOpen Access
A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations
2017· 3 citedOpen Access
A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles
2017· 83 citedOpen Access
The Drug Repurposing Hub: a next-generation drug library and information resource
Nature Medicine·2017· 1.1k cited
BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types
Nucleic Acids Research·2014· 24 citedOpen Access
An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries
Journal of Computer-Aided Molecular Design·2013· 12 citedOpen Access
Database-backed decision trees with application to biological informatics
Journal of Intelligent Information Systems·2007· 1 cited
Development of a digital fluorescence sensing technique to monitor the response of macrophages to external hypoxia
Journal of Biomedical Optics·2001· 17 citedOpen Access

Frequent Co-authors

David L. Lahr(8), Aravind Subramanian(7), Xiaodong Lü(7), Joshua Gould(7), Daniel D. Lam(7), Desiree Davison(7), Lev Litichevskiy(7), Rajiv Narayan(5), Todd R. Golub(5), Ryan Peckner(5), Shawn B. Egri(5), Tak Ko(5), Adam Officer(5), Malvina Papanastasiou(5), Vagisha Sharma(5), Jennie Z. Young(5), Steven A. Carr(5), Michael J. MacCoss(5), Li‐Huei Tsai(5), Jacob D. Jaffe(5)