M. Wienrich

Boehringer Ingelheim (Germany) — Germany

Neuroscience · Life Sciences

15h-index779citations33works0.02yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(20), Ion channel regulation and function(16), Retinal Development and Disorders(8), Neuroscience and Neural Engineering(5), Receptor Mechanisms and Signaling(4)

Publications33 total

The Broad‐Spectrum Cation Channel Blocker Pinokalant (LOE 908 MS) Reduces Brain Infarct Volume in Rats: A Temperature‐Controlled Histological Study
Basic & Clinical Pharmacology & Toxicology·2005· 5 citedOpen Access
Treatment with the selective muscarinic ml agonist talsaclidine decreases cerebrospinal fluid levels of Aβ<sub>42</sub>in patients with Alzheimer's disease
Amyloid·2003· 109 cited
Talsaclidine (WAL 2014 FU), a muscarinic M<sub>1</sub> receptor agonist for the treatment of Alzheimer's disease
Drug Development Research·2002· 17 cited
<i>In vivo</i> pharmacology of BIIR 561 CL, a novel combined antagonist of AMPA receptors and voltage‐dependent Na<sup>+</sup> channels
British Journal of Pharmacology·2001· 10 citedOpen Access
The AMPA receptor/Na+ channel blocker BIIR 561 CL is protective in a model of global cerebral ischaemia
European Journal of Pharmacology·2001· 4 cited
Pharmacodynamic profile of the M1 agonist talsaclidine in animals and man
Life Sciences·2001· 40 cited
Treatment with the Selective Muscarinic Agonist Talsaclidine Decreases Cerebrospinal Fluid Levels of Total Amyloid β‐Peptide in Patients with Alzheimer's Disease
Annals of the New York Academy of Sciences·2000· 53 cited
Characterization of the anticonvulsant and neuroprotectant BIIR 561 CL in vitro: effects on native and recombinant α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors
Naunyn-Schmiedeberg s Archives of Pharmacology·2000· 5 cited
Developmental regulation of AMPA-receptor properties in CA1 pyramidal neurons of rat hippocampus
Neuropharmacology·2000· 30 cited
BIIR 561 CL: a novel combined antagonist of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors and voltage-dependent sodium channels with anticonvulsive and neuroprotective properties.
PubMed·1999· 21 cited
BIIR 561 CL: A Novel Combined Antagonist of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptors and Voltage-Dependent Sodium Channels with Anticonvulsive and Neuroprotective Properties
Journal of Pharmacology and Experimental Therapeutics·1999· 10 cited
The Royal College of Surgeons Rat: An Animal Model for Inherited Retinal Degeneration with a Still Unknown Genetic Defect
Cells Tissues Organs·1998· 102 cited
Activation of a Cl−-Conductance by Protein Kinase-Dependent Phosphorylation in Cultured Rat Retinal Pigment Epithelial Cells
Experimental Eye Research·1998· 11 cited
De novo acquisition of neuronal polarity in retinoic acid-induced embryonal carcinoma cells.
PubMed·1997· 22 cited
Altered Regulation of Ion Channels in Cultured Retinal Pigment Epithelial Cells From Rcs Rats
1997
The effects of copper ions on glutamate receptors in cultured rat cortical neurons
Brain Research·1996· 92 cited
Interactions of the dye Evans Blue and GYKI 52466, a 2,3-benzodiazepine, with (S)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured rat cortical neurons: electrophysiological evidence for at least two different binding sites for non-competitive antagonists
Neuroscience Letters·1996· 9 cited
Activation of Cl − Currents in Cultured Rat Retinal Pigment Epithelial Cells by Intracellular Applications of Inositol-1,4,5-triphosphate: Differences Between Rats with Retinal Dystrophy (RCS) and Normal Rats
The Journal of Membrane Biology·1996· 33 cited
Investigations on the mechanism of action of the antiproliferant and ion channel antagonist flufenamic acid
Naunyn-Schmiedeberg s Archives of Pharmacology·1996· 10 cited
Neurowissenschaften bei Boehringer lngelheim
e-Neuroforum·1996
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Frequent Co-authors

Thomas Weiser(11), Olaf Strauß(10), Michael Wiederholt(5), Helmut A. Ensinger(5), Michael Brenner(5), Rainer Palluk(5), A. Raschig(4), Angelo Ceci(3), Alessia Maddalena(2), Wolfgang H. Oertel(2), Roger M. Nitsch(2), Stefan Mergler(2), Wolfram Gaida(2), Helmut Kettenmann(2), Min Zhou(2), Christian Steinhäuser(2), W. D. Bechtel(2), A. Brambilla(2), A. Sagrada(2), J. Harting(2)